Scleroderma Treated With Steroids Through Pregnancy, Cesarean Section and Puerperium

Raynaud's phenomenon and peripheral gangrene complicating scleroderma in pregnancy—diagnosis and management

“…Several drugs which are relatively contraindicated in pregnancy were proposed for treatment, such as ketanserin, d‐penicillamine (Lyle 1978), and captopril (Baethge & Wolf 1989). Corticosteroids (Hoffman & Diamond 1961) and colchicine (Guttadauria et al . 1977) are not contraindicated in pregnancy but were not sufficiently effective.…”

Scleroderma and Pregnancy

“…Literature describing the effect of scleroderma on the antepartum course of pregnancy and the management of labour with regional anaesthesia has been cited above. The body of knowledge specifically concerning the complications in these patients following Caesarean section is limited to case reports of pulmonary oedema (Hoffman and Diamond, 1967) and renal failure attributed to malignant hypertension (Ehrenfeld et al, 1977). In neither report was the type of anaesthesia mentioned.…”