“…9 11 As pathological alterations and clinical manifestations of SSc are a continuum, any subsetting model involving only the extent of skin changes seems arbitrary and restrictive. 12 Therefore, subsetting classification criteria that include the disease-specific autoantibodies and additional imaging such as nailfold capillaroscopy, validated in a cohort of patients with scleroderma and also with early disease, may aid the development of an optimal classification model.…”