Scleroderma Presenting as the Malabsorption Syndrome

Horswell, Richard R.; Hargrove, Marion D.; Peete, W. P.; Ruffin, Julian M.

doi:10.1016/s0016-5085(61)80143-1

Cited by 56 publications

(9 citation statements)

References 6 publications

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“…The most common of these diseases was scleroderma. The signs and symptoms in our first patient fulfil the criteria for the diagnosis of scleroderma (DiMarino et al 1973), and most of the histological changes seen in the small intestinal wall are similar to those previously described in association with that disease ( 1957, Rosenthal 1957, Horswell et al 1961, Hoskins et al 1962, Leneman et al 1962, Greenberger ef al. 1968, D'Angelo et al 1969, Schuffler et al 1978bSchuffler & Beegle 1979, Meuwissen et al 1982.…”

Section: Discussionsupporting

confidence: 82%

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Chronic intestinal pseudo‐obstruction in two patients. Overlap of features of systemic sclerosis and visceral myopathy

Venizelos¹,

Shousha²,

Bull³

et al. 1988

Histopathology

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Two patients with chronic intestinal pseudo-obstruction are reported, one of whom had definite systemic sclerosis while the other had certain manifestations of the disease. Biopsies of the small intestine revealed increased collagen and elastic fibres in the muscularis propria and subserosa in each case, while ganglion cells were normal. In addition, one patient had severe atrophy of the inner muscle layer and the other obvious vacuolation of the muscularis propria. Ultrastructural examination confirmed degeneration of the smooth muscle fibres. These latter features have been considered the hallmark of visceral myopathy and their finding in this patient therefore suggests that the different causes of pseudo-obstruction may not be completely demarcated and cases in which the features overlap may occur.

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Section: Discussionsupporting

confidence: 82%

“…X4700. 1957, Rosenthal 1957, Horswell et al 1961, Hoskins et al 1962, Leneman et al 1962, Greenberger ef al. 1968, D'Angelo et al 1969, Schuffler et al 1978bSchuffler & Beegle 1979, Meuwissen et al 1982.…”

Section: Discussionmentioning

confidence: 99%

Chronic intestinal pseudo‐obstruction in two patients. Overlap of features of systemic sclerosis and visceral myopathy

Venizelos¹,

Shousha²,

Bull³

et al. 1988

Histopathology

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“…Rodnan and Fennel first coined the term "progressive systemic sclerosis sine scleroderma" in 1962 (6). Only 31 additional patients with this variant have been reported in detail (6)(7)(8)(9)(10)(11)(12)(13)(14). We describe a large group of patients with ssSSc and com-pare them with patients diagnosed as having lcSSc.…”

Section: Conclusion Systemic Sclerosis Sine Scleroderma Should Be Inmentioning

confidence: 99%

Systemic sclerosis sine scleroderma: Demographic, clinical, and serologic features and survival in forty-eight patients

Poormoghim

Lucas

Fertig

et al. 2000

Arthritis & Rheumatism

243

103

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“…Unfortunately dilatation of the duodenum is not always present (Herrington, 1959;Horswell et al, 1961). Steatorrhoea Rosenthal (1957) presented four cases of progressive systemic sclerosis complicated by steatorrhoea, giving the details of one case coming to necropsy.…”

Section: Radiologymentioning

confidence: 99%

Steatorrhoea in Progressive Systemic Sclerosis (Scleroderma)

McBrien¹,

Mummery²

1962

BMJ

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Only half the stomach was removed. The importance of ligating the vasa brevia to reduce the gastric acidity is emphasized.Only one patient (0.8%) developed an anastomotic ulcer.The incidence of the dumping syndrome was much lower than with the standard three-quarters gastrectomy.Bile vomiting occurred in 23% of the series, but was severe in only one woman.Iron-deficiency anaemia was present in 65% of the men.Loss of weight occurred in 92% of the patients. There was no correlation between the result of the operation and the amount of weight lost.We are grateful to Miss Turner, M.A., the senior almoner, without whose help and ingenuity it would have been impossible to trace many of the patients. We are also indebted to the general practitioners of Oxford who also went to great trouble in helping us to find the patients.

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Scleroderma Presenting as the Malabsorption Syndrome

Cited by 56 publications

References 6 publications

Chronic intestinal pseudo‐obstruction in two patients. Overlap of features of systemic sclerosis and visceral myopathy

Chronic intestinal pseudo‐obstruction in two patients. Overlap of features of systemic sclerosis and visceral myopathy

Systemic sclerosis sine scleroderma: Demographic, clinical, and serologic features and survival in forty-eight patients

Steatorrhoea in Progressive Systemic Sclerosis (Scleroderma)

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