Scleredema adultorum treated with narrow‐band ultraviolet B phototherapy

Scleredema. A multicentre study of characteristics, comorbidities, course and therapy in 44 patients

“…Our study confirms that there is no single universally effective therapy for scleredema [8][9][10][11][12][13] . Physical therapies such as UVA1, bath PUVA, cream PUVA, low-dose broad-band UVA and narrow-band UVB [14][15][16][17][18] , localized electron beam therapy and photopheresis 19,20 , intravenous immunoglobulin (IVIg) [21][22][23] have been reported to improve the disease in anecdotal reports or small case series. Among the 19 patients of ours who received one systemic therapy, only two had a complete resolution, one with UVA1 and one with systemic steroids.…”

Scleredema Diabeticorum in a Patient with Type 2 Diabetes Mellitus

“…There is no comparative data and no approved algorithm for scleredema treatment. The efficiency of phototherapy, including UVA-1 treatment, PUVA therapy, narrow-band ultraviolet B phototherapy and photophoresis has been reported in the literature (20,21,22,23,24,25,26,27,28). In a few case reports, good results have been obtained with electron-beam therapy (29) and tamoxifen (30) therapy in scleredema diabeticorum.…”

Phototherapy for sclerosing skin conditions

“…A summary of the evidence available for the use of phototherapy in scleredema and necrobiosis lipoidica is presented in Table 5 as well [30,[66][67][68][69][70][71][72][73][74][75].…”