Scleredema adultorum. Not always a benign self-limited disease

Curtis, Arthur C.

doi:10.1001/archderm.92.5.526

Cited by 43 publications

(17 citation statements)

References 31 publications

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“…This induration may be preceded by a transient erythematous eruption, as occurred in our patient. 6 Thickening usually begins on the neck and later spreads to the shoulders, upper part of the trunk, and sometimes the face. Patients may complain of difficulty in opening their eyes and occasionally restrictive pulmonary disease may result, as it did in our patient.…”

Section: Commentmentioning

confidence: 99%

Scleredema of Buschke Successfully Treated With Electron Beam Therapy

Tamburin¹,

Peña²,

Meredith³

et al. 1998

Arch Dermatol

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Section: Commentmentioning

confidence: 99%

Scleredema of Buschke Successfully Treated With Electron Beam Therapy

Tamburin¹,

Peña²,

Meredith³

et al. 1998

Arch Dermatol

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“…Als eine weitere extrakutane Manifestation des Scleroedema ist in wenigen Fällen eine Augenbeteiligung beschrieben [5,23]. Bei unserem Patienten konnten Motilitätsstörungen beider Augen in alle Blickrichtungen festgestellt werden.…”

Section: Besprechungunclassified

“…Weitere extrakutane Manifestationen, die in der Literatur in Einzelberichten erwähnt werden und bei Herrn B. nicht vorlagen, sind eine Herzmuskelbeteiligung und eine Beteiligung der serösen Häute [5,20,22,27]. schen diesen Kollagenbündeln nachweisen [12].…”

Section: Besprechungunclassified

Scleroedema adultorum Buschke

Ulmer

Schaumburg-Lever

Bauer³

et al. 1998

Der Hautarzt

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Scleredema adultorum of Buschke is a rare disorder of unknown aetiology. It is characterized by diffuse, non-pitting swelling and induration of the skin. Skin biopsies reveal marked thickening of the dermis due to collagenous replacement of the subcutis and deposition of hyaluronic acid between the collagen fibers. The disease classically only affects the skin. In 24 cases an associated monoclonal gammopathy has been detected. A 75-year-old patient had a 19-year history of scleredema adultorum. In addition to a monoclonal gammopathy the patient suffered from involvement of the tongue, pharynx and upper esophagus. Furthermore a polyneuropathy, ocular involvement with restricted eye movements and a sicca syndrome were present. The simultaneous occurrence of cutaneous scleredema with any one of the above mentioned symptoms has been reported before. The wide variety of extracutaneous manifestations of scleredema as found in our patient is amazing and has not been previously described.

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“…A relatively underestimated complication of diabetes is scleroedema diabeticorum. It forms a distinct clinical entity and can be differentiated from scleroedema adultorum of Buschke, which develops at any age, frequently after an upper respiratory infection and spontaneously clears in months or years [2]. …”

Section: Introductionmentioning

confidence: 99%