Scleral remodeling during myopia development in mice eyes: a potential role of thrombospondin-1
Junhan Chen,
Shin-ichi Ikeda,
Yajing Yang
et al.
Abstract:Background
Scleral extracellular matrix (ECM) remodeling plays a crucial role in the development of myopia, particularly in ocular axial elongation. Thrombospondin-1 (THBS1), also known as TSP-1, is a significant cellular protein involved in matrix remodeling in various tissues. However, the specific role of THBS1 in myopia development remains unclear.
Method
We employed the HumanNet database to predict genes related to myopic sclera remodeling, fo… Show more
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