Sciscionella marina gen. nov., sp. nov., a marine actinomycete isolated from a sediment in the northern South China Sea

Tian, Xinpeng; Zhi, Xiao‐Yang; Qiu, Yunqi; Zhang, Yuqin; Tang, Shu‐Kun; Xu, Li-Hua; Zhang, Si; Li, Wen‐Jun

doi:10.1099/ijs.0.001982-0

Cited by 65 publications

(25 citation statements)

References 38 publications

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“…In recent years, more and more novel genera and species of marine actinomycetes have been isolated from sediments of the South China Sea, [1][2][3][4][5] suggesting South China Sea to be a rich source for exploring new marine actinomycete taxa. In the past two decades, marine actinomycetes are emerging as the most prolific new sources for novel drug discovery and have produced lots of secondary metabolites exhibiting excellent biological activities.…”

Section: Introductionmentioning

confidence: 99%

Lobophorins E and F, new spirotetronate antibiotics from a South China Sea-derived Streptomyces sp. SCSIO 01127

Niu

Chen

et al. 2011

J Antibiot

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The strain SCSIO 01127, isolated from the South China Sea sediment, was identified as a member of Streptomyces by the 16S rDNA sequence analysis. Two new spirotetronate antibiotics lobophorins E (1) and F (2), along with two known analogs lobophorins A (3) and B (4), were isolated from Streptomyces sp. SCSIO 01127. Their structures were elucidated on the basis of detailed IR, NMR and MS spectroscopic analyses. The new compound lobophorin F (2) showed antibacterial activities against Staphylococcus aureus ATCC 29213 and Enterococcus faecalis ATCC 29212 with MIC values of 8 mg ml À1 for both the strains, better than that of lobophorin B (4). Lobophorin F (2) also displayed better cytotoxic activities than lobophorin B (4), with IC 50 of 6.82, 2.93 and 3.16 mM against SF-268, MCF-7 and NCI-H460, respectively.

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Section: Introductionmentioning

confidence: 99%

Lobophorins E and F, new spirotetronate antibiotics from a South China Sea-derived Streptomyces sp. SCSIO 01127

Niu

Chen

et al. 2011

J Antibiot

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“…The members of this genus are well known for their production of novel secondary metabolites, such as salinosporamide A (NPI-0052) (Feling et al 2003); sporolides (Chauhan et al 2005); saliniquinone A-F (Murphy et al 2010) and salinosporamide K (Eustá-quio et al 2011). In 2009, we described another marine actinobacterial genus Sciscionella, which can tolerate high salt concentration (13 %) for growth (Tian et al 2009a). To date, more than 14 novel actinobacterial genera have been discovered from the marine environment (Goodfellow and Fiedler 2010;Kurahashi et al 2010;Chang et al 2011;Xiao et al 2011).…”

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confidence: 99%

Streptomyces oceani sp. nov., a new obligate marine actinomycete isolated from a deep-sea sample of seep authigenic carbonate nodule in South China Sea

Tian

Zhang

et al. 2012

Antonie van Leeuwenhoek

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A novel aerobic actinomycete strain, designated as SCSIO 02100(T), was isolated from a deep sea sediment sample collected from Northern South China Sea at a depth of 578 m. This isolate requires sea water or a sodium-supplemented medium for growth. BLAST searches based on the almost full length of the 16S rRNA gene sequence, showed that strain SCSIO 02100(T) had the highest similarities with Streptomyces armeniacus (JCM 3070(T)) (97.1 %). Phylogenetic trees reconstructed on the basis of 16S rRNA gene sequences revealed that strain SCSIO 02100(T) formed a distinct lineage with S. nanshensis SCSIO 01066(T) with 96.9 % similarity. Further analysis of the polyphasic taxonomic data, including morphological, phenotypic and chemotaxonomic properties, showed that strain SCSIO 02100(T) could be readily distinguished from the most closely related members of the genus Streptomyces. Thus, based on the polyphasic taxonomic data, a novel species, Streptomyces oceani sp. nov., is proposed, with the type strain SCSIO 02100(T) (=DSM 42043(T) = CGMCC 4.7007(T)).

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“…Currently, a large number of institutions around the world have developed research programs with the sole purpose of discovering new metabolites with pharmaceutical applications (Ellaiah et al 2004) for its use in the treatment of human illnesses, as well as those with biotechnological applications (Jemimah et al 2011). These studies have provided new knowledge of their taxonomy and description of new taxa, some of them without terrestrial counterparts (Olano et al 2009) and many with salt requirements such as Salinispora (Feling et al 2003, Maldonado et al 2005, Becerril-Espinosa et al 2013, Ng et al 2014, Serinicoccus (Yi et al 2004), Salinibacterium (Han et al 2005) and Sciscionella (Tian et al 2009). …”

Section: Introductionmentioning

confidence: 99%

Compounds isolated from Salinispora arenicola of the Gulf of California, México

Íñiguez‐Martínez

Cardoso-Martínez²,

Rosa

et al. 2016

Rev. biol. mar. oceanogr.

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Resumen.-La actinobacteria marina AMS370, identificada mediante comparación de las secuencias del gen 16S del ARNr como Salinispora arenicola, fue aislada a partir de sedimento del Golfo de California, México. De su extracto semi-polar, se aislaron 8 compuestos conocidos: ácido-4-Hidroxi-fenil acético (1), 5-Metil-2-metilen-2,3-dihidro-1H-pirimidin-4-ona (2), 1H-Pirimidin-2,4-diona (3), ácido-3-amino-5-hidroxi-benzoico (4), 2-(4-Amino-imidazol-[4,5-d]piridazin-1-il)-5-hidroximetil-4-metil-tetrahidrofuran-3-ol (5), Acrilato de 3-(4-Hidroxi-genil)-metilo (6), 3-Bencil-6-isobutil-piperazin-2,5-diona (7) y 5,8-epidioxi-(22E,24R)-ergosta-6,22-dien-3-ol (Peróxido de Ergosterol) (8). La identificación química fue realizada mediante comparación de sus espectros de RMN con los espectros de los compuestos originales. Ésta sería la primera ocasión que el compuesto 4 se reporta como un producto natural a partir del género Salinispora. El extracto crudo y todas sus fracciones fueron ensayadas contra Bacillus cereus, Escherichia coli, Enterococcus faecalis, Klebsiella pneumoniae, Proteus mirabilis, Staphylococcus aureus, Salmonella sp. y Candida albicans para probar su actividad antibiótica y antifúngica en el caso de la última especie. Asimismo se evaluó su actividad citotóxica frente a las líneas celulares de cáncer de mama (MCF-7), cervicouterino (HeLa) y colorectal (HCT-116). Solamente el extracto crudo semipolar y las fracciones 5.1 y 5.2 resultaron activas contra Klebsiella pneumoniae y Staphylococcus aureus. Palabras clave: Actinobacteria marina, actividad antibiótica, actividad citotóxica, Golfo de CaliforniaAbstract.-The marine actinobacterium AMS370, identified as Salinispora arenicola by 16S rRNA amplified gene comparison, was isolated from sediments of the Gulf of California, Mexico. From its semi-polar extract, 8 known compounds were isolated: 4-Hydroxy-phenyl acetic acid (1), 5-Methyl-2-methylene-2,3-dihydro-1H-pyrimidin-4-one (2), 1H-Pyrimidine-2,4-dione (3), 3-amino-5-hydroxy-benzoic acid (4), 2-(4-Amino-imidazol-[4,5-d]pyridazin-1-yl)-5-hydroxymethyl-4-methyl-tetrahydro-furan-3-ol (5), 3-(4-Hydroxy-phenyl)-acrylic acid methyl ester (6), 3-Benzyl-6-isobutyl-piperazine-2,5-dione (7) and 5,8-epidioxy-(22E,24R)-ergosta-6,22-dien-3-ol (Ergosterol peroxide) (8). The chemical identification was performed by comparison of their NMR spectra against the NMR spectra of the original compounds. This is the first time that compound 4 is reported as a natural product obtained from the Salinispora genus. The crude extract and all the fractions obtained were tested for antibiotic activity against Bacillus cereus, Escherichia coli, Enterococcus faecalis, Klebsiella pneumoniae, Proteus mirabilis, Staphylococcus aureus, Salmonella sp. and antifungic activity against Candida albicans. Also, breast cancer (MCF-7), cervical cancer (HeLa) and colorectal cancer cell lines (HCT-116) were tested to determine their cytotoxic activity. Only the semi-polar crude extract and its fractions 5.1 and 5.2 were active against Klebsiella pneumoni...

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Sciscionella marina gen. nov., sp. nov., a marine actinomycete isolated from a sediment in the northern South China Sea

Cited by 65 publications

References 38 publications

Lobophorins E and F, new spirotetronate antibiotics from a South China Sea-derived Streptomyces sp. SCSIO 01127

Lobophorins E and F, new spirotetronate antibiotics from a South China Sea-derived Streptomyces sp. SCSIO 01127

Streptomyces oceani sp. nov., a new obligate marine actinomycete isolated from a deep-sea sample of seep authigenic carbonate nodule in South China Sea

Compounds isolated from Salinispora arenicola of the Gulf of California, México

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