Scintillation Scanning in the Management of the Clinically Single Thyroid Nodule

Meadows, Paul M.

doi:10.1001/jama.1961.03040300001001

Cited by 62 publications

(11 citation statements)

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“…In the second group, only four cases with mild toxic symptoms were reported which proved benign on histology. This agrees well with the findings of Green (1957), although malignant hot nodules have been recorded by Meadows (1961) and others.…”

Section: Discussionsupporting

confidence: 93%

Thyroid nodules in Iraq

Al-Hashimi

1972

Postgraduate Medical Journal

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SummaryTwo groups of patients with solitary thyroid nodules have been analysed. One hundred patients of the first group under 20 years of age were managed conservatively with supplementary doses of thyroxin. Three hundred and thirty patients of the second group over the age of 20 were treated surgically.Seventeen percent of the first group had complete resolution of the thyroid nodule. The majority (eightythree patients) needed exploration for a residual lesion.In the two groups, adenomatous goitre constituted the most frequent pathological finding. True adenoma was the next in frequency.Malignant nodules were found in ten cases (3.0%°) of the second group; none was found in the first group. The overall incidence of carcinoma in solitary thyroid nodules in this study was 2 3°/.

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Section: Discussionsupporting

confidence: 93%

Thyroid nodules in Iraq

Al-Hashimi

1972

Postgraduate Medical Journal

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“…All of these tumours were small, less than one cm in diameter, and were all embedded in a hyperfunctioning nodule (Molnar, Childs and Woolner, 1958;Meadows, 1961). The present patient was found to have a papillary carcinoma in an autonomously functioning nodule.…”

Section: Discussionmentioning

confidence: 49%

Thyroid carcinoma in an autonomously hyperfunctioning thyroid nodule

Khan

Ell

MacLennan

et al. 1981

Postgraduate Medical Journal

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Summary A 44-year-old woman presented with hyperthyroidism and a nodule in her thyroid. 131I-scintigraphy of the gland showed concentration of the tracer within the nodule and suppressed activity in the rest of the gland. Histology of the resected thyroid proved the nodule to be a papillary carcinoma. The presence of carcinoma within an autonomous hyperactive thyroid in a patient with hyperthyroidism has been reported only rarely, and to the authors’ knowledge such a case has never been reported in Great Britain. Furthermore, unlike previously reported cases, the carcinoma was confined solely to the nodule.

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“…The following is a detailed report of our surprising results: the incidence of carcinoma (44%) in hot nodules was considerably higher than reported in previous studies [2][3][4][5][6][7][8][9][10][11] on AFTL or hot nodules on radioiodine scans.…”

Section: Introductionmentioning

confidence: 60%

Thyroid carcinoma m solitary hot thyroid lesions on Tc-99m sodium pertechnetate scans

et al. 1989

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Sixteen patients with nonsuppressible solitary hot thyroid lesions (SHTL) identified on T3 suppression images using Tc-99m sodium pertechnetate were studied over a period of 5 years. Of the 16 patients, 7 (44%) had papillary adenocarcinoma (PAC) and 9 (56%) had follicular adenoma (FA). Of the 7 patients with PAC, 3 were toxic and 4 nontoxic. Of the 9 patients with FA, 2 were toxic and 7 nontoxic. The Tl-201 chloride thyroid scans were useful in locating SHTL and revealing extranodular thyroid tissue. The echography was sensitive to visualization of the nodule structures. However, there were no significant differences between the clinical findings, radionuclide images, and echograms between for PAC and FA. All patients with PAC were treated by partial thyroidectomy and there were neither regional nor distant metastasis in any of them. In conclusion, our study provided the following extremely interesting result: SHTL in the present series have a higher incidence of malignancy than previously reported autonomously functioning thyroid lesions (AFTL). Histological examination is necessary for the diagnosis and management of SHTL and surgical treatment should be considered.

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Scintillation Scanning in the Management of the Clinically Single Thyroid Nodule

Cited by 62 publications

References 0 publications

Thyroid nodules in Iraq

Thyroid nodules in Iraq

Thyroid carcinoma in an autonomously hyperfunctioning thyroid nodule

Thyroid carcinoma m solitary hot thyroid lesions on Tc-99m sodium pertechnetate scans

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