Scintigraphic evaluation of gallbladder motor functions in H pylori positive and negative patients in the stomach with dyspepsia

Abstract

Yaylalı OT, Yılmaz M, Kıraç FS, Değirmencioğlu S, Akbulut M. Scintigraphic evaluation of gallbladder motor functions in H pylori positive and negative patients in the stomach with dyspepsia. World J Gastroenterol 2008; 14(9): 1406-1410 Available from: URL: http://www.wjgnet.com/1007-9327/14/1406.asp DOI: http://dx.doi.org/10.3748/wjg.14.1406 INTRODUCTIONThe H pylori infection is one of the most common chronic infections in humans [1,2] . The H pylori colonizing on the surface of the upper gastrointestinal mucosa is an interesting cause of active chronic gastritis and duodenitis or even gastric cancer worldwide [2][3][4][5][6][7] . The presence of H pylori infection could predispose to various disorders [8][9][10][11][12][13][14] . Dental disease might be associated with a higher recurrence of H pylori infection [9] . Some investigators have recently demonstrated the evidences that H pylori infection induced atherosclerosis and that H pylori-anti-heat-shock protein antibodies have been related to the prevalence of diseases such as coronary artery disease or cerebral infarction, resulted from atherosclerosis [10,11] . The H pylori may play a role in the pathogenesis of slow coronary flow via the elevation of homocysteine, and/or a possible disturbance in its metabolism [12] . The H pylori is present in about 67%-100% of duodenal ulcer patients and 13%-61% of normal population [15] . The H pylori infection can be diagnosed by invasive techniques requiring endoscopy and biopsy (eg, histological examination and culture) and by noninvasive techniques such as serology, urea breath test or detection of H pylori

Gallbladder function and dynamics of bile flow in asymptomatic gallstone disease

“…Hepatobiliary scintigraphy is used to show both morphological and physiological changes in the gallbladder. Since physiological changes usually precede morphological alterations by several weeks or months, there is great potential for early diagnosis by scintigraphy, before irreversible functional changes take place [6] . The main advantage of hepatobiliary scintigraphy is that the technique is noninvasive, quantitative, and reproducible and has a low interobserver error rate [7][8][9][10][11] .…”