Abstract:SummaryPiZZ-deficient patients affected by a severe panlobular emphysema were treated with an infusion of industrial concentrates of purified (XI -antitrypsin (AAT) . A treatment protocol was followed and the pharmacokinetic parameters were determined. The aim of this investigation was to consider the tissue distribution of AAT injected into untreated and treated patients, as well as into controls, in order to locate the labelled protein and map the kinetics of the protein deposit.Scintigraphies carried out on… Show more
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