Scientistsʼ Warning on Climate Change and Medicinal Plants

Applequist, Wendy L.; Brinckmann, J.A.; Cunningham, Anthony B.; Hart, Robbie; Heinrich, Michael; Katerere, David R.; Andel, Tinde van

doi:10.1055/a-1041-3406

Cited by 109 publications

(63 citation statements)

References 112 publications

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“…Therefore, the economic success of such high-value products depends on sustainable sourcing and production. The production of the materia prima currently faces ever-increasing challenges, including climatic instability, overexploitation, and poor management of the value chains [ 72 ].…”

Section: Discussionmentioning

confidence: 99%

Alkaloids Used as Medicines: Structural Phytochemistry Meets Biodiversity—An Update and Forward Look

2021

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Selecting candidates for drug developments using computational design and empirical rules has resulted in a broad discussion about their success. In a previous study, we had shown that a species’ abundance [as expressed by the GBIF (Global Biodiversity Information Facility)] dataset is a core determinant for the development of a natural product into a medicine. Our overarching aim is to understand the unique requirements for natural product-based drug development. Web of Science was queried for research on alkaloids in combination with plant systematics/taxonomy. All alkaloids containing species demonstrated an average increase of 8.66 in GBIF occurrences between 2014 and 2020. Medicinal Species with alkaloids show higher abundance compared to non-medicinal alkaloids, often linked also to cultivation. Alkaloids with high biodiversity are often simple alkaloids found in multiple species with the presence of ’driver species‘ and are more likely to be included in early-stage drug development compared to ‘rare’ alkaloids. Similarly, the success of an alkaloid containing species as a food supplement (‘botanical’) is linked to its abundance. GBIF is a useful tool for assessing the druggability of a compound from a certain source species. The success of any development programme from natural sources must take sustainable sourcing into account right from the start.

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Section: Discussionmentioning

confidence: 99%

Alkaloids Used as Medicines: Structural Phytochemistry Meets Biodiversity—An Update and Forward Look

2021

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“…In most developing countries, medicinal plants constitute the main materia medica for 70 to 95% of citizens [1][2][3]. Because of outdated medical facilities and unaffordable medical expenses, traditional medicinal plants have become the first choice or supplement for medical alternatives in most developing countries [4,5].…”

Section: Introductionmentioning

confidence: 99%

Ethnobotanical study on herbal market at the Dragon Boat Festival of Chuanqing people in China

Wang

Zhao

Chi

et al. 2021

J Ethnobiology Ethnomedicine

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Background The Chuanqing people (穿青人) are a linguistic group native to the Guizhou Province of China, with unique culture and rich knowledge of traditional medicinal plants. Herbal market at Dragon Boat Festival (DBF) plays an important role in the inheritance of traditional medicinal knowledge among the Chuanqing people. This study aims to record the profile of medicinal plants of the Chuanqing people, discuss the dilemmas faced by their inheritance, and propose some strategies for passing down information, which is critical for the inheritance and protection of the Chuanqing people’s traditional medical knowledge. Methods Data were collected through key informants and semi-structured interviews and free listing. Collected voucher specimens were identified using by botanical taxonomy method and deposited in the herbarium. Data were analyzed through use-value (UV) and cultural importance index (CI) values. Medicinal plants were compared with the Information System of Chinese Rare and Endangered Plants of the Chinese Academy of Sciences. Results were compared with the Pharmacopoeia of the People’s Republic of China (ChP), the Quality Standard of Traditional Chinese Medicine and National Medicine in Guizhou Province (QSG), and traditional medicines of Southeast Asian countries. Results A total of 102 species from 53 families and 92 genera were recorded, with Orchidaceae and Asparagaceae (six species each), and Berberidaceae and Asteraceae (five species each) as the predominant families. The whole plant (36%) was the most common medicinal part. Decoction (44%) was the most common preparation method. Seventy-one investigated human ailments were grouped into 12 categories. Diseases of the musculoskeletal system (34 mentions) were most frequently mentioned in this study. Moreover, the most frequently used taxon was Hedera sinensis (Tobler) Hand.-Mazz. (UV and CI = 0.29). The Chuanqing people’s medicine was highly similar to ChP and QSG. In comparison with Southeast Asian countries’ traditional medicines, except for the same preparation methods, the similarities in terms of medicinal ingredients, plants, and disease treatment were very low. Conclusions The herbal market at the DBF is an important platform for exchanging knowledge about the Chuanqing people’s traditional medicinal plants. The Chuanqing people’s traditional medicine is facing many challenges to its inheritance and development. To solve these problems, this study highlights the traditional medicinal knowledge of the Chuanqing people, providing basic data for further research and protection of minority medicine.

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“…In most developing countries, medicinal plants constitute the main materia medica for 70 to 95% of citizens [1][2][3]. Due to outdated medical facilities and unaffordable medical expenses, traditional medicinal plants have become the rst choice or supplement for medical alternatives in most developing countries [4,5].…”

Section: Introductionmentioning

confidence: 99%

An ethnobotanical study on the Chuanqing People of China based on an herbal market survey at the Dragon Boat Festival

Wang

Zhao

Chi

et al. 2021

Preprint

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Background: The Chuanqing (穿青人) are an ethnic group native to the Guizhou Province of China, with a unique culture and rich knowledge of traditional medicinal plants. The herbal market at the Dragon Boat Festival (DBF) plays an important role in the inheritance of traditional medicinal knowledge among the Chuanqing. This study aims to record the profile of medicinal plants of the Chuanqing, discuss the dilemmas faced by its inheritance and propose strategies. Such information is important for the inheritance and protection of the Chuanqing’s traditional medical knowledge. Methods: Data were collected through key informant interviews, semi-structured interviews and free listing. The collected voucher specimens were identified and deposited in the herbarium. The medicinal plants were compared with the Information System of Chinese Rare and Endangered Plants of the Chinese Academy of Sciences. The results were compared with those of the pharmacopeia of the People's Republic of China (ChP) and the Quality Standard of TCM, and National Medicine in Guizhou Province (QSG) and traditional medicines of Southeast Asian countries. Data were analyzed with use-value (UV) and cultural importance index (CI) values. Results: A total of 102 species from 53 families and 92 genera were recorded, with Orchidaceae and Asparagaceae (6 species each), Berberidaceae and Asteraceae (5 species each) as the predominant families. Whole plant (36%) was the most common medicinal part. Decoction (44%) was the most common preparation method. Seventy-one investigated human ailments were grouped into 12 categories. Diseases of the musculoskeletal system (34 mentions) were the most frequently mentioned in this study. Moreover, the most frequently used taxon was Hedera sinensis (Tobler) Hand.-Mazz. (UV and CI=0.29). A total of 9 medicinal plants were recorded in the Information System of Chinese Rare and Endangered Plants of the Chinese Academy of Sciences. The Chuanqing’s medicine had high similarity with ChP and QSG. While it had a high similarity in preparation method, and low similarity in medicinal parts, plant families and disease treatments with traditional medicines in Southeast Asian countries.Conclusions: The traditional herbal market at the DBF is an important platform for communicating traditional medicinal plant knowledge of the Chuanqing. There are some differences and connections between the Chuanqing's medicine, Chinese traditional medicines, and traditional medicines in Southeast Asian countries. The Chuanqing's traditional medicine is facing many difficulties in the inheritance and development. More scientific research and policies planning are needed to solve it. This study highlights the traditional medicinal knowledge of the Chuanqing, providing basic data for further research on and protection of minority medicine.

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Scientistsʼ Warning on Climate Change and Medicinal Plants

Cited by 109 publications

References 112 publications

Alkaloids Used as Medicines: Structural Phytochemistry Meets Biodiversity—An Update and Forward Look

Alkaloids Used as Medicines: Structural Phytochemistry Meets Biodiversity—An Update and Forward Look

Ethnobotanical study on herbal market at the Dragon Boat Festival of Chuanqing people in China

An ethnobotanical study on the Chuanqing People of China based on an herbal market survey at the Dragon Boat Festival

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