Scientific validation of a traditional toothpaste formulation to treat halitosis

Abstract

Since the beginning of human history, Cuminum cyminum seeds are habitually used in several cuisines of different food cultures. In India it is used in both whole and ground form as a traditional ingredient to make innumerable dishes without knowing their medicinal uses and properties. In Kerala, the decoction of the cumin seeds made from drinking water used for drinking purpose instead of ordinary water and in Tamilnadu cumin seeds used in daily to make food items called Rasam(soup) to eat with rice to increase the digestion. The fruits of Solanum lycopersicum are one of the important savoury vegetables used to increase the flavour of cooked foods. The oil and solid albumen ripe of Cocos nucifera (L.) fruits are commonly used in cooking and frying. Hence in the present study, the composition (paste) prepared by mixing of 2 drops of Solanum lycopersicum fruit juice, 2 drops of Cocos nucifera (L.) and 1gram of Cuminum cyminum seed powder were tested on the 100 subjects who are felt bad breath. The result of the present study showed effectively controlled bad breath in 91 patients even after on weak period of clinical trial and except 09 diabetic patients.

FTIR screening of phytocompounds in plant Spermacoce hispida L. of Vallimalai Hills at Vellore district

“…Peaks at 2772.17 (medium H-C=O: C-H Stretching) for the presence of aldehyde showed a mere similarity with peaks at 1844.8 for Andrographis echioides [25] . Peaks at 1812.76 (weak C-H bending) for the presence of aromatic compound has a concordance with peaks at 1864.83 for Cocos nucifera, at 1895.68, 184.22 and 1833.97 for Cumin cymiun, Solanum lycoperisicum and Cocusnusifera [26] 1836, 86 Tephrosia purpurea [27] . The peak at 1730.8 (Strong C=O stretching) indicates the existence of α, β-unsaturated ester, which resembles peaks at 1720.19 for Cardiospermum halicacabum [28] .…”

“…The peak at 3037.34 (medium C-H stretching) exhibit the presence of bioactive compounds alkenes have a strong resemblance with methanol leaf extract of Annonas quamosa [24] . The spectral peaks at 2954.41, 2923.56 2879.2 (medium C-H Stretching), 1455.99 (medium C-H bend) and 723.175 (medium C-H rock)for alkanes have mere similarity with the peaks at 2995.87, 2954.41, 2923.56, 2848.35 and 2875.34 for methanol leaf extract of Andrographis echioides [25] , peaks at 2991.05, 2921.63, 2873 and 42, 2856 for methanol leaf extract of Cumin cyminum [26] , peaks at 2923.36, 2879.2 and 2855.1 for methanol leaf extract of Tephrosia purpurea [27] , peaks at 2925.48 and 2856.06 for methanol leaf extract of Cardiospermum halicacabum [28] , peaks at 2991.05, 2873.42 and 2856.06 for the methanol leaf extract of Cumin cyminum [29] . Peaks at 2848.35 (strong boroad N-H stretching) indicates the presence of amine salt has a concordance with the peak at 2770.24 observed for Cumin cyminum [29] .…”

“…Absorption peaks at 1702.84 (strong C=O stretching) indicates that Conjugated aldehyde has a concordance with similar results observed for peaks at 1698.98 in Cardiospermum halicacabum [28] . Peaks at 1671.98 (weak C=C stretching), 1651.73 (medium C=C stretching), 1606.41 (medium C=C stretching) and 830.205 (medium C=C bending) indicates the presence of bioactive phytocompounds alkene and conjugated alkene which have some similarity with peaks observed at 822.491, 712.569 for alkenes in Andrographis echioides [25] , at 3008.41 for Cumin cymiun, Solanum lycoperisicum and Cocusnusifera [26] , at 1627.63,1654.62, 977.733, 806.099 and 888.059 for Tephrosia purpurea [27] , 1656.77, 832.133, 800.314 and 710.64 for Cardiospermum halicacabum [28] , at 1606.41 for Conjugated alkene in Tephrosia purpurea [27] , at 1634.38, 1603.52 in Andrographis echioides [25] . Spectral peaks at 1410.67 (strong S=O stretching) for sulfonyl chloride has a close resemblance with Sulfonyl chloride in Cardiospermum halicacabum at 1408.75 [28] , 1380.141 C.cyminum [29] .…”

“…Spectral peaks at 1520.6 (strong N-O asymmetric stretch) for nitro-compound showed a similarity with Nitro compounds in Andrographis echioides at peaks 1513.85, 1486.85 [25] , in Tephrosia purpurea at 1504.2, 1531.2 and 1482.99 [27] , in Cardiospermum halicacabum at 1522.52, 1478.17 and 1498.42 [28] . Spectral peaks at 1379.82 (medium O-H bending) for Phenol has a close resemblance with phenol in C.cyminum at 1322.93 [29] in Andrographis echioides at 1386.57, 1311.36 [25] , in Cumin cymiun, Solanum lycoperisicum and Cocusnusifera at 1325.82 [26] .Peaks at 1328.71(strong C-N stretching) for aromatic amine has a close relationship with aromatic amine in Tephrosia purpurea at 1324.86 [27] , in Cumin cymiun, Solanum lycoperisicum and Cocusnusifera at 1236.15 [26] . Peaks at1249.65 (strong C-O stretching) for alkyl aryl ether showed a close similarity with Alkyl aryl ether in C.cyminum at 1246.75 [29] in Andrographis echioides at 1228.43 [25] .…”

“…Peaks at1249.65 (strong C-O stretching) for alkyl aryl ether showed a close similarity with Alkyl aryl ether in C.cyminum at 1246.75 [29] in Andrographis echioides at 1228.43 [25] . Peaks 211.08 (strong C-O stretching) forvinyl ether has strong concordant with vinyl ether in Andrographis echioides at 1204.33 [25] , in Cumin cymiun, Solanum lycoperisicum and Cocusnusifera at 1225.54, 1208.18 and 1205.29 [26] , in Tephrosia purpurea at1204.33 [27] . The pectral peaks at1166.72 (strong C-O stretching) forester has a strong similarity withester in Cardiospermum halicacabum at1190.83, 1170.58 [28] , in Tephrosia purpurea at 1184.08 [25] , in Andrographis echioides at 1184.08 [25] .…”