Abstract:Over 3000 patients were randomized in a four-way trial that tested whether various doses of metoclopramide gave additional benefit to dexamethasone prophylaxis. The addition of 50 mg metoclopramide produced the lowest rate of postoperative nausea and vomiting (14·5 per cent). There were no differences to the procedure, or complication rates during follow-up to 53 months in this trial that included 139 patients. Early results were better with the Ligasure procedure in this trial that included 84 procedures. The… Show more
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