Scientific Opinion on the safety and efficacy of straight‐chain primary aliphatic alcohols/aldehydes/acids, acetals and esters with esters containing saturated alcohols and acetals containing saturated aldehydes (chemical group 1) when used as flavourings for all animal species

Feed, EFSA Panel on Additives and Products or Substances used in Animal

doi:10.2903/j.efsa.2013.3169

Cited by 31 publications

(32 citation statements)

References 22 publications

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“…Toxicological data for subchronic studies, from which NOAEL values could be derived, were available for octyl acetate [09.007] and ethyl acetate [09.001] in CG 1 (EFSA FEEDAP Panel, 2013 ), 2‐ethylhexan‐1‐ol [02.082] in CG 2 (EFSA FEEDAP Panel, 2012a ), citral [05.020] in CG 3 (EFSA FEEDAP Panel, 2016a ), linalool [02.013] and terpineol 28 [02.230] in CG 6 (EFSA FEEDAP Panel, 2012b ), 1,8‐cineole in CG 16 (EFSA FEEDAP Panel, 2012e , 2021a ), eugenol [04.003] and trans ‐anethole [04.010] in CG 18 (EFSA FEEDAP Panel, 2011 ), cinnamaldehyde [05.014] in CG 22 (EFSA FEEDAP Panel, 2017 ), benzyl alcohol [02.010] (EFSA FAF Panel, 2019 ) and methyl salicylate [09.749] in CG 23 (EFSA FEEDAP Panel, 2012f ), benzene‐1,3‐diol [04.047] in CG 25 (EFSA FEEDAP Panel, 2012g ), 1‐methoxy‐4‐methylbenzene [04.015] in CG 26 (EFSA FEEDAP Panel, 2012h ), myrcene [01.008] and β‐caryophyllene in CG 31 (EFSA FEEDAP Panel, 2016b ), and β‐caryophyllene oxide in CG 32 (EFSA CEF Panel, 2014 ).…”

Section: Assessmentmentioning

confidence: 99%

Safety and efficacy of a feed additive consisting of an essential oil from the flowers of Cananga odorata (Lam.) Hook.f. & Thomson (ylang ylang oil) for use in all animal species (FEFANA asbl)

Bampidis¹,

Azimonti²,

Bastos³

et al. 2022

EFS2

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Following a request from the European Commission, the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of an essential oil from the flowers of Cananga odorata (Lam.) Hook.f. & Thomson (ylang ylang oil), when used as a sensory additive in feed and water for drinking for all animal species. The FEEDAP Panel concluded that the essential oil under assessment is safe up to the maximum proposed use levels in complete feed of 1 mg/kg for chickens for fattening, 1.5 mg/kg for laying hens, turkeys for fattening and rabbits, 2 mg/kg for piglets, 2.5 mg/kg for pigs for fattening, 3 mg/kg for sows, 4.5 mg/kg for cattle for fattening, sheep, goats and horses, 5 mg/kg for veal calves (milk replacer), fish, dogs and ornamental fish. For cats, the calculated safe concentration in complete feed is 1 mg/kg feed. The FEEDAP Panel considered that the use in water for drinking is safe provided that the total daily intake of the additive does not exceed the daily amount that is considered safe when consumed via feed. No concerns for consumer safety were identified following the use of the additive up to the maximum proposed use level in feed. The essential oil under assessment should be considered as irritant to skin and eyes, and as a skin and respiratory sensitiser. The use of the additive in animal feed under the proposed conditions of use was not expected to pose a risk for the environment. Ylang ylang oil is recognised to flavour food. Since its function in feed would be essentially the same as that in food, no further demonstration of efficacy is considered necessary.

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Section: Assessmentmentioning

confidence: 99%

Safety and efficacy of a feed additive consisting of an essential oil from the flowers of Cananga odorata (Lam.) Hook.f. & Thomson (ylang ylang oil) for use in all animal species (FEFANA asbl)

Bampidis¹,

Azimonti²,

Bastos³

et al. 2022

EFS2

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“…In previous opinions of the FEEDAP Panel (EFSA FEEDAP Panel, 2012a , b , c , 2013 , 2016a , b , 2019a , b , 2020a , b ), the 37 additives under assessment were fully characterised, with the exception of ethyl oleate [09.192], and evaluated for their safety and efficacy as flavouring substances. Ethyl oleate was excluded from further assessment.…”

Section: Assessmentmentioning

confidence: 99%

“…Ethyl oleate [09.192] belongs to chemical group 01. In its previous assessment, the FEEDAP Panel was unable to perform an assessment of the safety of ethyl oleate for the target species, the consumer and the environment because of insufficient purity (EFSA FEEDAP Panel, 2013 ). The applicant has now provided analytical data which include the full characterisation of the additive and show compliance with the proposed specification.…”

Section: Assessmentmentioning

confidence: 99%

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Safety of 37 feed additives consisting of flavouring compounds belonging to different chemical groups for use in all animal species (FEFANA asbl)

Bampidis¹,

Azimonti²,

Bastos³

et al. 2022

EFS2

View full text Add to dashboard Cite

Following a request from the European Commission, the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the supplementary information submitted on the safety of 37 compounds belonging to different chemical groups, when used as sensory additives (flavourings) in feed for all animal species formerly assessed by the Panel in the context of the re‐evaluation of these feed additives. The FEEDAP Panel concludes that ethyl oleate [09.192] and benzyl cinnamate [09.738] are safe at the proposed use level of 5 mg/kg complete feed for all animal species, the consumer and the environment; ethyl salicylate [09.748] is safe up to the maximum proposed use level of 5 mg/kg complete feed for all animal species and the consumer. No new data were submitted on the safety for the user that would allow the FEEDAP Panel to change its previous conclusion for 26 out of the 37 compounds under assessment. The use of 4‐terpinenol [02.072], linalyl butyrate [09.050], linalyl formate [09.080], linalyl propionate [09.130], linalyl isobutyrate [09.423], isopulegol [02.167] and 1,2‐dimethoxy‐4‐(prop‐1‐enyl)‐benzene [04.013] as flavouring additives at the proposed use level of 5 mg/kg in feed for all animal species is considered safe for the environment. The use of 3‐methyl‐2‐cyclopenten‐1‐one [07.112] at 0.5 mg/kg and methyl dihydrojasmonate [09.520] at 5 mg/kg in feed for all animal species except marine animals is considered safe for the environment.

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“…Toxicological data of subchronic studies, from which NOAELs could be derived, were available for octyl acetate [09.007] in CG 1 (EFSA FEEDAP Panel, 2013 ), citral [05.020] in CG 3 (EFSA FEEDAP Panel, 2016a ), citronellol [02.011] in CG 4 (EFSA FEEDAP Panel, 2016b ), terpineol 32 [02.230] and linalool [02.013] in CG 6 (EFSA FEEDAP Panel, 2012a ), l‐carvone [07.147] in CG 8 (EFSA FEEDAP Panel, 2016c ), myrcene [01.008], d‐limonene [01.045], p ‐cymene [01.002] and β‐caryophyllene [01.007] in CG 31 (EFSA FEEDAP Panel, 2015 , 2016d ).…”

Section: Assessmentmentioning

confidence: 99%

Safety and efficacy of feed additives consisting of expressed sweet orange peel oil and its fractions from Citrus sinensis (L.) Osbeck for use in all animal species (FEFANA asbl)

Additives¹,

Bampidis²,

Azimonti³

et al. 2021

EFS2

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Following a request from the European Commission, the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of expressed sweet orange oil and its fractions obtained from the fruit peels of Citrus sinensis (L.) Osbeck, when used as sensory additives (flavourings) in feed and water for drinking for all animal species. The presence of perillaldehyde was identified as a source of potential concern. However, in target species fed citrus by-products as part of daily feed, the use of the expressed orange oil and its fractions was not expected to increase the exposure to perillaldehyde to a relevant extent (< 10%). For dogs, cats, ornamental fish and ornamental birds not normally exposed to citrus by-products, no conclusion can be drawn. For the other species, the FEEDAP Panel concluded that the additives under assessment are safe at the maximum proposed use levels in complete feed. The FEEDAP Panel considered that the use in water for drinking is safe provided that the total daily intake of the additive does not exceed the daily amount that is considered safe when consumed via feed. No concerns for consumer safety were identified following the use of the additives up to the maximum proposed use level in feed. The additives under assessment should be considered as irritants to skin and eyes, and as skin and respiratory sensitisers. The use of the additives under the proposed conditions of use in animal feed was not expected to pose a risk for the environment. Expressed orange oil and its fractions were recognised to flavour food. Since their function in feed would be essentially the same as that in food, no further demonstration of efficacy was considered necessary.

show abstract

Scientific Opinion on the safety and efficacy of straight‐chain primary aliphatic alcohols/aldehydes/acids, acetals and esters with esters containing saturated alcohols and acetals containing saturated aldehydes (chemical group 1) when used as flavourings for all animal species

Cited by 31 publications

References 22 publications

Safety and efficacy of a feed additive consisting of an essential oil from the flowers of Cananga odorata (Lam.) Hook.f. & Thomson (ylang ylang oil) for use in all animal species (FEFANA asbl)

Safety and efficacy of a feed additive consisting of an essential oil from the flowers of Cananga odorata (Lam.) Hook.f. & Thomson (ylang ylang oil) for use in all animal species (FEFANA asbl)

Safety of 37 feed additives consisting of flavouring compounds belonging to different chemical groups for use in all animal species (FEFANA asbl)

Safety and efficacy of feed additives consisting of expressed sweet orange peel oil and its fractions from Citrus sinensis (L.) Osbeck for use in all animal species (FEFANA asbl)

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