Scientific and technological prospection on transdermal formulations and complementary therapies for the treatment of primary dysmenorrhea

Dias, Sávia Francisca Lopes; Pereira, Lívia Carvalho; Oliveira, Aldeídia Pereira de; Santos, Rivaldo Vital dos; Nunes, Lívio César Cunha

doi:10.1080/13543776.2019.1562547

Cited by 15 publications

(7 citation statements)

References 35 publications

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“…Primary dysmenorrhea, a common gynecologic problem among women of reproductive age, is characterized by painful uterine cramps that occur before or during menstruation ( 1 , 2 ). Women with dysmenorrhea are usually felt pain in the lower part of the abdomen without any pelvic diseases (i.e., endometriosis, pelvic inflammatory disease, uterine leiomyoma, or intrauterine contraceptive device) ( 3 ). Dysmenorrhea has even been considered a genuine chronic pain condition, occurring on a regular basis for most women.…”

Section: Introductionmentioning

confidence: 99%

Significant Increase in Depression in Women With Primary Dysmenorrhea: A Systematic Review and Cumulative Analysis

Zhao

Wu²,

Kang

et al. 2021

Front. Psychiatry

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Women with primary dysmenorrhea are vulnerable to develop a depressive disorder, which is a common form of psycho-disturbance. However, clinical findings are inconsistent across studies, and the evidence has not been previously synthesized. This study aims to investigate whether primary dysmenorrhea is associated with a higher risk of depression via a cumulative analysis. Four electronic databases were systematically searched for the eligible studies. The combined effect was assessed by analyzing the relative risk (RR) and standard mean differences (SMD) with a 95% confidence interval (CI). This cumulative analysis was registered on the PROSPERO (ID: CRD42020169601). Of 972 publications, a total of 10 studies involving 4,691 participants were included. Pooled results from six included studies showed that primary dysmenorrhea was associated with a significant depressive disorder (RR = 1.72, 95%CI: 1.44 to 2.0, P < 0.001; heterogeneity: I2 = 0%, P = 0.544). In addition, synthesis results from two studies provided the BDI scores suggested that dysmenorrhea had significantly higher scores when compared to non-dysmenorrhea (SMD = 0.47, 95% CI: 0.31–0.62, P < 0.001; heterogeneity: I2 = 0%, P = 0.518). However, in the two studies providing the PROMIS T-Score, the pooled result showed that there was no significant difference between women with dysmenorrhea and those without dysmenorrhea (P = 0.466). The overall quality of the evidence in our study was judged to MODERATE. The present study has confirmed the positive relationship between primary dysmenorrhea and depression. Social supports and medical help from pain management physicians or psychologists are important interventions for women with dysmenorrhea-suffering depressive disorder.

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Section: Introductionmentioning

confidence: 99%

Significant Increase in Depression in Women With Primary Dysmenorrhea: A Systematic Review and Cumulative Analysis

Zhao

Wu²,

Kang

et al. 2021

Front. Psychiatry

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“…Besides, more study on possible effective treatments is demanded because of the existing limited research. 13 …”

Section: Discussionmentioning

confidence: 99%

“…Besides, more study on possible effective treatments is demanded because of the existing limited research. 13 However, the limitation of this study must be considered. The study was based on WOS database, not including all the related papers in this field, so the literature is incomplete.…”

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confidence: 93%

Scientific Knowledge Graph of Dysmenorrhea: A Bibliometric Analysis from 2001 to 2021

Fang,

Liu,

Wang

et al. 2023

JPR

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Purpose This study aims to help researchers master the most active hotspots and trends quickly through bibliometric analysis in the field of dysmenorrhea. Methods We retrieved literature on Web of Science from 2001 to 2021, and bibliometric analysis software CiteSpace was used in combination with VOSviewer. Results We finally acquired 944 papers and an upward trend in articles continued in this field overall. Through the map, China contributed the most, followed by the USA and Turkey. For institutions, Beijing University of Chinese Medicine in China contributed the most, followed by National Yang-Ming University in Taiwan, China. Hsieh JC and Hellman KM were both the most prolific authors with 14 articles. Five major research groups, respectively, with Hsieh JC, Hellman KM, Zhu J, Liang F and Dun W were the key group. Dawood MY was the most dominant author and most frequently cited author. The Cochrane Database of Systematic Reviews Journal was the most productive, and the Fertility and Sterility Journal was the most cited. Advances in pathogenesis and management for primary dysmenorrhea written by Dawood MY was most cited and influential. Pathophysiology, the potential central mechanism, syndrome, evaluation index, diagnosis of adenomyosis-associated dysmenorrhea, treatment, etc., were the main trends and hotspots. Conclusion Dysmenorrhea research has received a lot of attention from scholars. Strengthening international cooperation may promote the development of this field. The pathophysiology of dysmenorrhea, its impact on public health and its treatment are current research hotspots and are likely to be the focus of future study.

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“…7 Over the last 10 years, CAM therapies have been proposed, especially in regions of Africa and Asia where traditional medicine remains trusted by the majority of patients, therefore, approximately all studies conducted regarding CAM efficacy originated from these countries. 2,8,9 Physical activity, for instance yoga, aromatherapy, psychotherapy, and other forms of relaxation, vitamins and dietary changes, acupressure and acupuncture are just few of the proposed lifestyle targeted therapies in cases of PD. 3 This review focuses on lifestyle changes that could potentially result in minimizing symptoms of PD and in improving overall QoL for these patients, by providing current scientific evidence on their efficacy.…”

Section: Introductionmentioning

confidence: 99%

Integrating Lifestyle Focused Approaches into the Management of Primary Dysmenorrhea: Impact on Quality of Life

Tsonis¹,

Gkrozou

Barmpalia³

et al. 2021

IJWH

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Objective: This narrative review aims to identify alternative ways to improve the symptoms of primary dysmenorrhea (PD). Background: PD refers to endometrial painful cramps during the premenstrual period. This condition affects a lot of women worldwide and is accompanied with absenteeism and high economic costs, thus, risk-free, and effective therapeutic approaches are needed. Pharmacological agents such as non-steroidal anti-inflammatory drugs (NSAIDs) and oral contraceptive pills (OCPs), which are widely prescribed for these women, demonstrate adequate efficacy in alleviating pain and discomfort. The long natural course of the disease dictates remedies that focus on lifestyle changes and on improvement of Quality-of-Life (QoL) for women suffering with PD. Materials and Methods: Five major search engines, namely MEDLINE, PubMed, EMBASE, and Cochrane Library were searched for articles published prior to October 2020 focused in PD. A total of 74 paper were included. Discussion: Physical activity, for instance yoga, aromatherapy massage, and other forms of relaxation, vitamins and dietary changes, acupressure and acupuncture,a and some psychological interventions are just few of the proposed health behavior targeted approaches in cases of PD. This review focuses on lifestyle changes and alternative methods that could potentially result in minimizing symptoms of PD and in improving overall QoL for these patients, by providing current scientific evidence on their efficacy. Conclusion: Complementary and alternative medicine practices (CAM) are widely accepted by women. International literature provides controversial scientific evidence, thus further studies need to be conducted in order to prove or disregard their efficacy in cases of PD.

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Scientific and technological prospection on transdermal formulations and complementary therapies for the treatment of primary dysmenorrhea

Cited by 15 publications

References 35 publications

Significant Increase in Depression in Women With Primary Dysmenorrhea: A Systematic Review and Cumulative Analysis

Significant Increase in Depression in Women With Primary Dysmenorrhea: A Systematic Review and Cumulative Analysis

Scientific Knowledge Graph of Dysmenorrhea: A Bibliometric Analysis from 2001 to 2021

Integrating Lifestyle Focused Approaches into the Management of Primary Dysmenorrhea: Impact on Quality of Life

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