Schwannome intraventriculaire: à propos d'un cas

Fourth Ventricular Schwannoma: Identical Clinicopathologic Features as Schwann Cell-Derived Schwannoma with Unique Etiopathologic Origins

“…It is often not considered in the differential diagnosis of fourth ventricular tumors due to the rarity of occurrence. It is usually difficult to identify intraventricular schwannomas on neuroimaging because it lacks specific imaging characteristics to differentiate them from other intraventricular tumors [1, 2, 9, 16]. In our case for example, the differential diagnoses consisted of ependymoma, subependymoma, choroid plexus papilloma, or pilocytic astrocytoma.…”

“…One such theory is neoplastic transformation of neural crest cells that were displaced during embryogenesis [2, 4, 5, 9, 15, 16]. Schwann cells are derived from the neural crest, and it is possible that a few of these cells could become trapped within the neural tube as it closes and undergoes differentiation during embryonic development.…”

Supratentorial intraventricular schwannoma of the choroid plexus

“…Therefore, the occurrence of a nerve sheath tumour in central nervous tissue is unexpected 1.2 . There are eleven case reports of ventricular schwannomas 3,[7][8][9] . The majority of these were located in either the lateral or fourth ventricles [4][5][6][7] .…”

“…The majority of these were located in either the lateral or fourth ventricles [4][5][6][7] . Most reported intraventricular schwannomas have been benign, with only two demonstrating malignant features 7,8 (Table).…”

“…As the autonomic nerves are associated with Schwann cells, this has led to the theory that primary intraventricular schwannomas may arise from the autonomic nervous tissue of the plexus choroids [3][4][5][6][7][8] . It has also been suggested that intra-axial schwannomas could arise from neural crest cells displaced into the nervous system as a result of failed migration in embryonic life 1 .…”