Schwannoma of the stomach with elevated preoperative serum carbohydrate antigen 19-9: report of a case

Fukuchi, Minoru; Naitoh, Hiroshi; Shoji, Hisanori; Yamagishi, Junko; Suzuki, Masaki; Yanoma, Toru; Kiriyama, Shinsuke; Kuwano, Hiroyuki

doi:10.1007/s00595-011-0066-8

Cited by 9 publications

(5 citation statements)

References 14 publications

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“…As a result, we believe that most GS are benign tumors that will not recur, but there are a few malignant possibilities. The histological criteria for the diagnosis of malignant schwannoma are based on mitotic map and the presence of nuclear atypia [ 20 ]. When the mitotic rate is greater than 10 / 50 high power field, it needs to be followed up regularly like other malignant tumors [ 21 ].…”

Section: Discussionmentioning

confidence: 99%

Clinicopathological study of gastric schwannoma and review of related literature

Zhong

Liu

et al. 2022

BMC Surg

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Background This study aimed to investigate the clinical features, diagnostic criteria, treatment options, and prognosis of patients with gastric schwannoma (GS). Methods We collected the clinical data of all patients pathologically diagnosed with GS in Zhejiang Provincial People's Hospital from May 2012 to October 2021. Results A total of 26 cases of GS were analyzed clinicopathologically, where the sizes of the tumor were found to be in the range of 1–6 cm (mean: 3.16 cm, median: 3.05 cm). A computed tomography (CT) scan analysis revealed that most masses were either moderately progressive or uniformly enhanced. According to ultrasound gastroscopy results, most of them were hypoechoic masses. There were 23 cases of surgery and three cases of endoscopic submucosal tumor dissection. Immunohistochemistry demonstrated that S100 was positive in 26 patients, immunomarker SOX10 was positive in five, whereas CD34, CD117, and SMA were negative in most patients. CK (Pan), Dog-1, and Desmin were also found negative. All 26 cases were followed up after the conclusion of the study where no evidence of recurrence or metastasis was observed. Conclusions GS is a unique form of peripheral schwannoma. The diagnosis of this type of tumor depends on the pathology and immunohistochemistry of the individual. The key to treating this type of tumor is endoscopy and surgery. Follow up and related literature review showed that GS was a benign tumor with little possibility of malignant transformation.

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Section: Discussionmentioning

confidence: 99%

Clinicopathological study of gastric schwannoma and review of related literature

Zhong

Liu

et al. 2022

BMC Surg

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“…Recently, Yang et al [21] reported a case of gastroduodenal intussusception due to GS, which, to the best of our knowledge, is the only case reported in English literature. In addition, we found only 1 case in which the patient initially presented with elevated serum carbohydrate antigen 19-9 preoperatively [22]. …”

Section: Discussionmentioning

confidence: 99%

Gastric Schwannoma: A Tumor Must Be Included in Differential Diagnoses of Gastric Submucosal Tumors

Feng-jie

Zhu

et al. 2017

Case Reports in Gastrointestinal Medicine

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Gastric schwannoma (GS) is a rare neoplasm of the stomach. It accounts for 0.2% of all gastric tumors and is mostly benign, slow-growing, and asymptomatic. Due to its rarity, GS is not widely recognized by clinicians, and the precise differential diagnosis between GS and other gastric submucosal tumors remains difficult preoperatively. The present study reports a case of GS misdiagnosed as gastrointestinal stromal tumor and reviews the clinical, imaging, and pathological features, treatment, and follow-up of 221 patients with GS previously reported in the English literature. Although GS is rare, the case reported in the current study highlights the importance of including GS in differential diagnoses of gastric submucosal tumors. Furthermore, the findings of the review suggest that although many cases are asymptomatic, the most common symptoms are abdominal pain or discomfort, not gastrointestinal bleeding, and malignant GSs present with clinical symptoms more commonly. Although large-sample multicenter studies on the efficacy, safety, and oncological outcomes of minimally invasive techniques are required, the findings presented herein may be helpful for clinicians when diagnosing or treating GS.

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“…Schwannomas often occur in fourth and fifth decade and has a 1.6:1 female predilection. They are found in varied locations as the brachial plexus and the sciatic nerve [3,4,[9][10][11] . Schwannoma are slow-growing and they don't traverse the nerve but remain in sheath lying on top of it.…”

Section: Discussionmentioning

confidence: 99%

An interesting case of Schwannoma left hand: Case report

Annamalai¹,

Selvam²,

Rekha³

2020

Int. J. Surg. Sci.

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Schwannoma is a tumor of tissue covers nerves called the nerve sheath. It is a common type of benign peripheral nerve tumor in adults can occur anywhere in the body at any age. It typically arises from single bundle (fascicle) within the main nerve and displaces the rest of nerve.Here we present a case of swelling in the left hand for the past 6 years. Increasing in size in the last 3 months. Came with the complaints of numbness over the little finder and half of the ring finger for the past 3 months. No restricted movements in the finger. Imaging done showed soft tissue sarcoma without any nerve involvement. Patient underwent local excision. HPE revealed as Schwannoma.

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Schwannoma of the stomach with elevated preoperative serum carbohydrate antigen 19-9: report of a case

Cited by 9 publications

References 14 publications

Clinicopathological study of gastric schwannoma and review of related literature

Clinicopathological study of gastric schwannoma and review of related literature

Gastric Schwannoma: A Tumor Must Be Included in Differential Diagnoses of Gastric Submucosal Tumors

An interesting case of Schwannoma left hand: Case report

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