Schwannoma of the colon mimicking carcinoma: a case report and literature review

Braumann, Chris; Guenther, Nina; Menenakos, Charalambos; Junghans, T.

doi:10.1007/s00384-006-0264-9

Cited by 20 publications

(21 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In the gastrointestinal system they more frequently arise from the Auerbach’s plexus than from Meissner's 4. The cells of the schwannoma are immunoreactive to S-100 protein and vimentin, but are negative for SMA, desmin, CD 117, P53, myoglobulin and pan CK 3 4 9. In the differential diagnosis of gastrointestinal stromal tumour, it shows positivity to CD117 and CD34 but negativity to S-100 protein 10…”

Section: Discussionmentioning

confidence: 99%

Schwannoma of the sigmoid colon

et al. 2015

View full text Add to dashboard Cite

Colonic schwannomas are very rare gastrointestinal tumours originating from Schwann cells, which form the neural sheath. Primary schwannomas of the lower gastrointestinal tract are very rare and usually benign in nature. However, if they are not surgically removed, malign degeneration can occur. We report a case of a 79-year-old woman who presented to our clinic with rectal bleeding and constipation. She underwent a lower gastrointestinal tract endoscopy. A mass subtotally obstructing the lumen of the sigmoid colon was seen and biopsies were taken. Histopathological examination indicated a suspicion of gastrointestinal tumour and the patient underwent sigmoid colon resection after preoperative evaluation by laboratory analysis, abdominal ultrasonography and CT. Her postoperative course was uneventful and she was discharged on the fifth day for outpatient control. The histopathology report revealed schwannoma of the sigmoid colon. This was a case of schwannoma of the sigmoid colon that was successfully treated with total resection.

show abstract

Section: Discussionmentioning

confidence: 99%

Schwannoma of the sigmoid colon

et al. 2015

View full text Add to dashboard Cite

show abstract

“…It has been estimated that schwannomas represent only 2%-6% of all stromal tumors of the gastrointestinal tract [5]. Stomach and small intestine are the most common sites for schwannomas [4,5,6], and primary schwannomas of the colon are extremely rare [2,4]. The most common location for schwannoma of the large intestine is cecum, followed by sigmoid colon, transverse colon, descending colon, and rectum [4].…”

Section: Discussionmentioning

confidence: 99%

“…Even though intracranial schwannoma is relatively common, primary schwannoma of the colon is rare [1,2,3,4,6] and a few cases of colonic schwannoma have been reported [2,3,4,5,6]. Herein, we report a case of vestibular schwannoma and metachronous schwannoma of the colon.…”

Section: Introductionmentioning

confidence: 98%

See 1 more Smart Citation

Metachronous schwannoma in the colon with vestibular schwannoma

et al. 2014

View full text Add to dashboard Cite

We experienced a case of vestibular schwannoma and metachronous schwannoma in the colon. A 59-year-old female presented with a 1-month history of hematochezia. She had undergone suboccipital craniectomy resulting in radical subtotal resection, followed by gamma knife radiosurgery for a large left vestibular schwannoma 4 years prior to admission. On preoperative colonoscopy, a huge mass through which the colonoscope could not be passed was detected. CT scans showed colo-colonic intussusception with a 4.8-cm-sized mass in the descending colon. PET/CT revealed hypermetabolism of the descending colon tumor and pericolic lymph nodes. We performed left hemicolectomy under the preoperative impression of colon cancer with intussusception. A pathological diagnosis of benign schwannoma of the colon was made in this patient.

show abstract

“…The stomach is the most common site for schwannomas in the gastrointestinal tract, occurring primarily in the gastric submucosa, followed by the colon (2,3). The most infrequently affected sites are the small intestine and esophagus (4,5).…”

Section: Introductionmentioning

confidence: 99%

Gastric schwannoma misdiagnosed as GIST: A case report with immunohistochemical and molecular study

et al. 2016

View full text Add to dashboard Cite

Abstract. Schwannomas are tumors derived from Schwann cells. Generally, they are benign and their typical site of origin is the subcutaneous tissue of the distal extremities or of the head and neck region. Gastrointestinal localization of schwannomas is extremely rare, and the stomach is the prevalent site. The present study describes the case of a gastric schwannoma in a 61-year-old male who underwent subtotal gastrectomy following a clinical diagnosis of a gastrointestinal stromal tumor (GIST). A histological, immunohistochemical and molecular study was performed to exclude the misdiagnosis of GIST. The histomorphological features of the lesion and absence of c-Kit and PDGFRA mutations indicated the diagnosis of gastric schwannoma.

show abstract

Schwannoma of the colon mimicking carcinoma: a case report and literature review

Cited by 20 publications

References 0 publications

Schwannoma of the sigmoid colon

Schwannoma of the sigmoid colon

Metachronous schwannoma in the colon with vestibular schwannoma

Gastric schwannoma misdiagnosed as GIST: A case report with immunohistochemical and molecular study

Contact Info

Product

Resources

About