Schwannoma of nasal septum: A rare case report with literature review

Mitra, Bhaskar; Debnath, Sharmistha; Paul, Biswanath; Pal, Mallika; Banerjee, T.J.; Saha, Tarak Nath

doi:10.1016/j.ejenta.2012.08.002

Cited by 7 publications

(14 citation statements)

References 18 publications

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“…MRI is also useful in cases with intracranial extension. 3 On MRI, schwannomas may typically appear isointense in T1-weighted sequences and hyperintense in T2-weighted sequences. These radiological features may be variable in few cases so need correlation with clinical and histopathological features.…”

Section: Discussionmentioning

confidence: 99%

“…Nasal schwannomas are presumed to be arising from the sheath of the ophthalmic and maxillary branches of the trigeminal nerve and autonomic ganglia. 3 Neoplasm can be sporadic or associated with neurofibromatosis 2. Nasal masses have variable differential diagnosis like nasal polyp, rhinosporidiosis, rhinoscleroma, nasal tuberculosis, angiofibroma, neurifibroma, inverted papilloma, meningioma, nasal glioma, encephalocele rarely neurilemmoma.…”

Section: Discussionmentioning

confidence: 99%

“…A sinonasal schwannoma can be found at different sites, including the nasal septum, tip of the nose, turbinate, paranasal sinus and nasopharynx. [3][4][5] Ethmoidal sinus is most common site amongst sinuses. Nasal schwannomas are presumed to be arising from the sheath of the ophthalmic and maxillary branches of the trigeminal nerve and autonomic ganglia.…”

Section: Discussionmentioning

confidence: 99%

“…2 Cases with nasal schwannoma arising from nasal septum and inferior turbinate have been reported. 3,4 Nasal schwannoma has no age or sex predilection.…”

Section: Introductionmentioning

confidence: 99%

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A Rare Case of Nasal Schwannoma of Middle Turbinate

Sathe

Shelke

Marfatia

et al. 2016

Surgical Techniques Development

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Schwannoma is a benign, slow-growing nerve sheath tumor derived from the Schwann cells. Cases with nasal schwannoma arising from nasal septum and inferior turbinate have been reported, though being rare. A 32-yearold male patient presented to our hospital with left side progressive nasal blockage since 4 months and multiple episodes of epistaxis. Anterior rhinoscopy revealed left side smooth spherical nasal mass, which was bleeding on touch. Computed tomography was done, which was suggestive of right side deviated nasal septum. Left nasal cavity soft tissue lesion extended into anterior ethemoid cells, causing widening of the osteomeatal complex. The patient underwent endoscopic excision of nasal mass. Histopathology of nasal mass suggested nasal schwannoma. Though nasal schwannoma is rare, it should be considered as a differential diagnosis in case of unilateral nasal mass with epistaxis. Definitive diagnosis of schwannoma can be considered only after final histopathological reporting of the surgical specimen.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

“…2 Cases with nasal schwannoma arising from nasal septum and inferior turbinate have been reported. 3,4 Nasal schwannoma has no age or sex predilection.…”

Section: Introductionmentioning

confidence: 99%

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A Rare Case of Nasal Schwannoma of Middle Turbinate

Sathe

Shelke

Marfatia

et al. 2016

Surgical Techniques Development

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“…Schwannoma is a benign encapsulated nerve sheath tumor composed of entirely well-differentiated Schwann cells. [1,2] This entity was first described by Verocay in 1908. Stout coined the term neurilemmoma.…”

Section: Introductionmentioning

confidence: 99%

Right Ethmoidal Sinus Schwannoma: Case Report of a Common Entity with an Unusual Presentation

Kavitha

Swapna

Kumarguru

et al. 2020

Ann of Pathol and Lab Med

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Schwannomas are benign, encapsulated nerve sheath tumors arising from Schwann cells. Approximately, 25-40% of all Schwannomas occur in the head and neck region, acoustic nerve being the most frequent site. The tumors originating from nasal cavity or paranasal sinuses are rare and constitutes only four percent. A 40-year-old male presented with history of blurred vision of right eye and protrusion of right eye ball since 6 months. It was associated with history of watering and redness. Examination of right eye revealed mild proptosis and ptosis. Computed Tomography [CT] scan showed a large expansile cystic lesion measuring about 5.2x5.6x6.5cm involving entire right ethmoidal sinus. It showed expansion into anterior cranial fossa, roof and medial wall of right orbit. Radiological opinion suggested mucocele of right ethmoidal sinus. Intra-operatively, tissue specimen was sent for squash smear cytology. Cytology smears showed features suggestive of spindle cell tumor. Possibility of Schwannoma was considered. The specimen was subsequently subjected to histopathological examination. Microscopy showed tumor tissue composed of tumor cells arranged in alternate hypercellular and hypocellular pattern. Hypercellular areas showed occasional verocay bodies. Hypocellular areas showed loosely arranged spindle shaped tumor cells. Histopathological features were suggestive of Schwannoma. On Immunohistochemistry (IHC), neoplastic cells were positive for S-100 and negative for EMA. Ethmoidal sinus schwannoma extending into anterior cranial fossa is an unusual presentation. Clinically, it poses a diagnostic dilemma. Squash smear cytology is challenging, but helpful in establishing the correct diagnosis. Histopathology is confirmatory and immunohistochemistry is supportive.

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