Schwangerschaft und Immunsystem - I. Immunologische Charakterisierung lymphoider Zellen in der Spätschwangerschaft

Abstract

Lymphocyte preparations obtained from peripheral blood of 36 healthy pregnancy women during the last 4 weeks of gestation were tested for various cell surface markers (E-, EA- EAC-rosettes, surface Ig positive cells). 29 healthy, non-pregnant age matched women served as controls. The cell surface marker analysis did not show significantly different results in the two groups tested except diminished percentages of EA-rosettes in the pregnancy group. EA-rosettes-forming cells (Fc-receptor positive cells) are known to the effectors of spontaneous and antibody dependent lymphocytotoxicity. Therefore, slightly depressed lymphocytotoxicity may be expected during late pregnancy.

Yeast-based nucleotide supplementation in mother sows modifies the intestinal barrier function and immune response of neonatal pigs

“…In addition, intestinal sIgA represents an important mucosal surface defines for resisting their entry into the lumen ( Zhu and Wang, 2017 ). Nucleotides are important for the development of immune organs ( Li et al., 2019 ), and late pregnancy is an important period for the development of immune cells and system in foetus ( Heidenreich et al., 1981 ). Thus, maternal YN supplementation during late pregnancy may be beneficial for the development of immune cells and system in neonatal piglets, and in enhancing the expression of pro-inflammatory and anti-inflammatory cytokines in piglets before birth ( Pié et al., 2004 ).…”