School Performance and Theophylline

Abstract

In Reply.— Drs Weinberger, Lindgren, and Joad's comments are appreciated, and they raise a number of questions about our report of the adverse effects of theophylline. We appreciate their concerns, and we hope the following satisfies them. Because the manuscript was published in Pediatrics and reported by the staff of USA Today, we will concern ourselves with the peer-reviewed published paper. The study was randomized and double blinded; the investigators, the children, the teachers, and the parents had no way of knowing whether the children were on theophylline or not, and there was no prior experience with theophylline titration.