Schockraummanagement

Krueger, Antonio; Frink, Michael; Kießling, Andreas; Ruchholtz, Steffen; Kühne, Christian

doi:10.1007/s00104-012-2384-9

Cited by 18 publications

(3 citation statements)

References 32 publications

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“…Hypothermia is known to negatively influence coagulation and haemostasis [ 45 ]. As a result, several guidelines for the treatment of polytrauma patients recommend normothermia and argue to avoid core temperatures below 34 °C [ 46 , 47 ]. Kishi and co-workers’ study points towards an additional physiologic response to hypothermia that might even negatively influence the cerebral blood flow during haemorrhagic shock [ 31 ].…”

Section: Discussionmentioning

confidence: 99%

A Systematic Review of Neuroprotective Strategies during Hypovolemia and Hemorrhagic Shock

Nistor

Behringer

Schmidt

et al. 2017

IJMS

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Severe trauma constitutes a major cause of death and disability, especially in younger patients. The cerebral autoregulatory capacity only protects the brain to a certain extent in states of hypovolemia; thereafter, neurological deficits and apoptosis occurs. We therefore set out to investigate neuroprotective strategies during haemorrhagic shock. This review was performed in accordance to the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. Before the start of the search, a review protocol was entered into the PROSPERO database. A systematic literature search of Pubmed, Web of Science and CENTRAL was performed in August 2017. Results were screened and evaluated by two researchers based on a previously prepared inclusion protocol. Risk of bias was determined by use of SYRCLE’s risk of bias tool. The retrieved results were qualitatively analysed. Of 9093 results, 119 were assessed in full-text form, 16 of them ultimately adhered to the inclusion criteria and were qualitatively analyzed. We identified three subsets of results: (1) hypothermia; (2) fluid therapy and/or vasopressors; and (3) other neuroprotective strategies (piracetam, NHE1-inhibition, aprotinin, human mesenchymal stem cells, remote ischemic preconditioning and sevoflurane). Overall, risk of bias according to SYRCLE’s tool was medium; generally, animal experimental models require more rigorous adherence to the reporting of bias-free study design (randomization, etc.). While the individual study results are promising, the retrieved neuroprotective strategies have to be evaluated within the current scientific context—by doing so, it becomes clear that specific promising neuroprotective strategies during states of haemorrhagic shock remain sparse. This important topic therefore requires more in-depth research.

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Section: Discussionmentioning

confidence: 99%

A Systematic Review of Neuroprotective Strategies during Hypovolemia and Hemorrhagic Shock

Nistor

Behringer

Schmidt

et al. 2017

IJMS

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“…The management of such injuries is quite crucial and our aim in this article is to show that simultaneous fixation of all the fractures is beneficial and gives good results. Patient’s age, other associated injuries, and comorbidities should be examined closely [ 2 ].…”

Section: Introductionmentioning

confidence: 99%

A Case of Symmetrical Bilateral Bifocal Femur Fracture with Bilateral Patella Fracture – A Case Report!

Pradhan,

Altaf,

Attarde

et al. 2023

jocr

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Introduction: Bilateral bifocal femur fractures occur as a result of high-velocity trauma mainly road traffic accidents with dashboard injuries or fall from height. These fractures can result in high morbidity or mortality as they are usually presented with hypovolemic shock or fatal fat embolism syndrome. Case Report: We present a 47-year-old male with a history of fall from 35 feet. He sustained a symmetrical intertrochanteric femur fracture with a diaphyseal femur fracture with a bilateral patella fracture. There was no evidence of any head injury or spinal fracture. The patient reached the emergency room in hypotension and was maintaining saturation on room air. The patient was admitted to the intensive care unit; hypotension was corrected overnight and was operated on after 24 h with bilateral intramedullary long proximal femoral nail and tension band wiring for the bilateral patella fractures. At 1-year follow-up, he was able to do his daily activities with minimal limitation. Conclusion: Bilateral bifocal femur fractures result from a high-velocity trauma. In such injuries, careful evaluation of all the systems should be performed to find out concomitant injuries. Single-staged surgical intervention decreases the morbidities of the subsequent surgeries, helps in a rehabilitation hospital stay as well as financially suitable for the patient. Keywords: Bilateral, bifocal femur, intertrochanteric, diaphyseal.

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“…Abbreviated Injury Scale (AIS) (ausMutschler et al 2004 [9]). den nachrangigen "Secondary Survey", bei dem dann alle weiteren auch nicht lebensbedrohlichen Verletzungen diagnostiziert werden sollen[10].Vorhandene Befunde müssen klar an alle an der Versorgung Beteiligte kommuniziert werden. "Primary Survey" zur Beurteilung und Sicherung der Vitalfunktionen nach ATLS-Protokoll (aus[19], mod.…”

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