Frozen section (FS) analysis is widely used for ovarian and endometrial cancers and plays a key role in intraoperative decisions.However, what is its diagnostic value, and is it necessary for all endometrial cancer patients? The present study aimed to explore these questions.Endometrial cancer is one of the most common gynecologic cancers. The most common histotype is endometrioid cancer (EC). 1 A preoperative diagnosis of endometrial cancer is made by dilatation and curettage, endometrial biopsy, or hysteroscopic biopsy. The accuracy of preoperative and final pathology results varies from 60% to 80%, 2,3 and according to a study of 1804 patients, the κ value is only 0.52, 4 indicating moderate agreement.