Schmerztherapie bei Osteoporose

Heuchemer, L; Emmert, Dorian; Bender, Tim; Rasche, Tim; Marinova, Milka; Kasapovic, Adnan; Conrad, Rupert; Mücke, Martin

doi:10.1007/s00132-020-03898-5

Cited by 3 publications

(1 citation statement)

References 26 publications

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“…Hu et al [28] injected Zoledronic Acid intravenously before PVP and found that patients with the combination method had advantages of longterm pain relief, increased bone density and lower risk of refracture. On the other hand, osteoporosis was associated with back pain independently, which signi cantly reduced the quality of life [29,30].…”

Section: Discussionmentioning

confidence: 99%

Continuity and Volume of Bone Cement and Anti Osteoporosis Treatment were Guarantee of Good Clinical Outcomes for Percutaneous Vertebroplasty: a Multicentre Study

Cheng,

Ren,

et al. 2024

Preprint

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Background: As the most prevalent fragility fracture caused by osteoporosis, increasing attention was paid to vertebral compression fractures (VCF) day by day. Percutaneous vertebroplasty (PVP) had unique advantages in treatment of VCF and was used widely. Researching how to improving surgical efficacy and decreasing postoperative residual was able to benefit more patients. The purpose of our study was to seek for those associated factors with good clinical outcomes after PVP and provide evidence for improving surgical efficacy. Material and Methods: 186 patients who underwent PVP from January 2021 to January 2023 were reviewed retrospectively in the study. The patients were divided into two groups according to clinical outcomes. Preoperative general data and surgical data were collected for statistical analysis. Multivariate logistic regression analysis and the receiver operating characteristic curve were used to identify the associated factors with good clinical outcomes. Results: There were statistically significant differences between two groups in volume of bone cement (p=0.012), standardized treatment for osteoporosis (p=0.004)and bone cement continuity (p=0.006). The associated factors with good clinical outcomes after PVP were continuous bone cement (OR=2.237, 95% CI=1.191-4.201, p=0.012), standardized treatment for osteoporosis (OR=2.105, 95% CI=1.089-4.068, p=0.027) and volume of bone cement >5.5ml (OR=1.271, 95% CI=1.023-1.579, p=0.030). Conclusion: PVP effectively released the back pain of patients and was worthy of promotion. However, postoperative residual pain was an important factor that reduced the clinical outcomes. Continuous bone cement, Injected bone cement >5.5ml and tandardized treatment for osteoporosis were guarantee of good clinical outcomes for PVP

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Section: Discussionmentioning

confidence: 99%

Continuity and Volume of Bone Cement and Anti Osteoporosis Treatment were Guarantee of Good Clinical Outcomes for Percutaneous Vertebroplasty: a Multicentre Study

Cheng,

Ren,

et al. 2024

Preprint

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How relevant is lumbar bone mineral density for the stability of symphyseal implants? A biomechanical cadaver study

Schwaabe¹,

Gleich²,

Linhart³

et al. 2021

Eur J Trauma Emerg Surg

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Purpose Osteoporotic bone tissue appears to be an important risk factor for implant loosening, compromising the stability of surgical implants. However, it is unclear whether lumbar measured bone mineral density (BMD) is of any predictive value for stability of surgical implants at the pubic symphysis. This study examines the fixation strength of cortical screws in human cadaver specimens with different BMDs. Methods The lumbar BMD of ten human specimens was measured using quantitative computed tomography (qCT). A cut-off BMD was set at 120 mg Ca-Ha/mL, dividing the specimens into two groups. One cortical screw was drilled into each superior pubic ramus. The screw was withdrawn in an axial direction with a steady speed and considered failed when a force decrease was detected. Required force (N) and pull-out distance (mm) were constantly tracked. Results The median peak force of group 1 was 231.88 N and 228.08 N in group 2. While BMD values differed significantly (p < 0.01), a comparison of peak forces between both groups showed no significant difference (p = 0.481). Conclusion Higher lumbar BMD did not result in significantly higher pull-out forces at the symphysis. The high proportion of cortical bone near the symphyseal joint allows an increased contact of pubic screws and could explain sufficient fixation. This condition is not reflected by a compromised lumbar BMD in a qCT scan. Therefore, site-specific BMD measurement could improve individual fracture management.

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