Schizophrenia and Depression: A systematic Review of the Effectiveness and the Working Mechanisms Behind Acupuncture

Bosch, Peggy; Noort, Maurits van den; Staudte, Heike; Lim, Sabina

doi:10.1016/j.explore.2015.04.004

Cited by 31 publications

(33 citation statements)

References 103 publications

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“…In future research, therefore, the inclusion of follow-up actiwatch data would be useful. Moreover, future studies with large, randomized (placebo), controlled, clinical trials are needed [13] in order to replicate the preliminary acupuncture effects that were found in the present study and in order to answer the question whether acupuncture has an independent effect on improving cognition or whether the improved cognition is secondary to improved sleep. Furthermore, taking a closer look at the gender issue would be particularly interesting [33] in order to investigate whether male patients with chronic schizophrenia and sleep disorders show the same beneficial acupuncture effects as the present female patient suffering from chronic schizophrenia and sleep disorders did.…”

Section: Discussionmentioning

confidence: 99%

“…One relatively new nonpharmacological intervention technique in Western psychiatry is acupuncture, which is an old Eastern medicine treatment technique [13]. To date, not much research has been conducted on the use of acupuncture as an add-on intervention technique in the treatment of patients suffering from schizophrenia [13], and almost no research at all exists on the use of acupuncture in the treatment of their comorbid sleep disorders [14].…”

Section: Introductionmentioning

confidence: 99%

“…To date, not much research has been conducted on the use of acupuncture as an add-on intervention technique in the treatment of patients suffering from schizophrenia [13], and almost no research at all exists on the use of acupuncture in the treatment of their comorbid sleep disorders [14]. However, the scarce research to date shows sleep-ameliorating effects of acupuncture in the treatment of sleep disorders in schizophrenia [13]. Therefore, in this study, the use of acupuncture for the add-on treatment of comorbid sleep disorders in a patient with chronic schizophrenia is investigated further by using both psychological-test and actiwatch data.…”

Section: Introductionmentioning

confidence: 99%

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Acupuncture in the Treatment of a Female Patient Suffering from Chronic Schizophrenia and Sleep Disorders

Bosch

Lim

Lee

et al. 2016

Case Reports in Psychiatry

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Background. The use of acupuncture in the treatment of sleep disorders in patients with chronic schizophrenia is investigated. Case Presentation. We report the case of a 44-year-old female outpatient of German origin who had been suffering from long-term schizophrenia and sleep disorders. The patient was treated with manual acupuncture weekly for 12 weeks, and a psychological assessment was performed before, immediately after, and three months after the acupuncture treatment period. In addition, actiwatch data were collected for 14 days both before and after the acupuncture treatment period. Conclusion. Acupuncture treatment led to a decrease in general psychopathology, less severe sleep problems, and markedly improved cognitive functioning (working memory) in the patient; however, the positive and the negative symptoms remained stable. The actiwatch data revealed a beneficial effect of acupuncture, showing better sleep latency, a trend towards better sleep efficiency, and a decrease in the number of minutes that the patient was awake during the night after acupuncture treatment. In sum, this study showed that acupuncture might be beneficial in the treatment of sleep disorders in patients suffering from chronic schizophrenia, but future, large, randomized (placebo), controlled, clinical trials are needed in order to replicate the present preliminary findings.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Acupuncture in the Treatment of a Female Patient Suffering from Chronic Schizophrenia and Sleep Disorders

Bosch

Lim

Lee

et al. 2016

Case Reports in Psychiatry

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“…Heterogeneity: chi 2 = 11.20, df = 9 (P = 0.26); I 2 = 20% Test for overall effect: Z = 7.92 (P < 0.00001) Heterogeneity: chi 2 = 20.44, df = 13 (P = 0.08); I 2 = 36% Test for overall effect: Z = 8.21 (P < 0.00001) Test for subgroup differences: chi 2 =5.94, df = 1 (P = 0.01); I 2 = 83.2% Evidence-Based Complementary and Alternative Medicine [49][50][51][52]. It is generally believed that the LPNN is related to sleep and emotions.…”

Section: Subtotal (95% Ci)mentioning

confidence: 99%

Effectiveness and Safety of Acupuncture for Perimenopausal Depression: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials

Xiao

Zhang

Yao

et al. 2020

Evidence-Based Complementary and Alternative Medicine

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Objective. To determine the effectiveness and safety of acupuncture for perimenopausal depression. Methods. We searched the Cochrane Central Register of Controlled Trials, PubMed, EMBASE, CNKI, VIP Citation Databases, Wan Fang, and online trial registries such as ClinicalTrials.gov for randomized controlled trials (RCTs) assessing the efficacy and safety of acupuncture for perimenopausal depression. Literature screening, data extraction, and determination of the risk of bias were performed by two researchers independently. The extracted data were pooled and meta-analyzed using RevMan5.3 software. Results. In total, 16 RCTs covering 1311 patients were enrolled. Overall, the results showed that acupuncture was more effective in the treatment of perimenopausal depression than antidepressants (OR = 2.68, 95% CI (1.84, 3.90), P<0.00001). Furthermore, HAMD scores in the manual acupuncture group and electroacupuncture group were lower than those of antidepressants (manual acupuncture vs. antidepressants (MD = −2.35, 95% CI (−2.93, −1.77), P<0.00001) and electroacupuncture vs. antidepressants (MD = −1.2, 95% CI (−1.92, −0.48), P=0.001)). Data analysis revealed that the treatment effect of acupuncture was more stable than that of antidepressants (MD = −2.4, 95% CI (−3.37, −1.43), P<0.00001). Moreover, acupuncture was safer than antidepressants based on the incidence of adverse events (OR = 0.23, 95% CI (0.1, 0.52), P=0.0004). But acupuncture has no effect on estrogen levels (P≥0.05). Conclusions. Acupuncture for perimenopausal depression is safe and effective. Moreover, it has more stable long-term effects than antidepressants and hormone replacement therapy (HRT). We recommend acupuncture as a clinical treatment of perimenopausal depression.

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“…Die Prävalenz der Krankheit liegt bei Frauen höher als bei Männern [2] und die Symptomatik ist bei Frauen und Männern unterschiedlich ausgeprägt [3]. Als Therapie werden meistens Medikamente [4] und Psychotherapie [5] eingesetzt, aber heutzutage auch immer öfter Akupunktur als Zusatzbehandlung [6]. Das Ziel dieser Studie ist es, zu untersuchen, ob und, wenn Ja, welche Geschlechtsunterschiede es bei der Akupunkturbehandlung von Patienten mit Depressionen gibt.…”

Section: Geschlechtsunterschiede Bei Der Akupunkturbehandlung Von Patunclassified

Geschlechtsunterschiede bei der Akupunkturbehandlung von Patienten mit Depressionen

Bosch

Lim

Staudte³

et al. 2019

Dtsch Z Akupunkt

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Schizophrenia and Depression: A systematic Review of the Effectiveness and the Working Mechanisms Behind Acupuncture

Cited by 31 publications

References 103 publications

Acupuncture in the Treatment of a Female Patient Suffering from Chronic Schizophrenia and Sleep Disorders

Acupuncture in the Treatment of a Female Patient Suffering from Chronic Schizophrenia and Sleep Disorders

Effectiveness and Safety of Acupuncture for Perimenopausal Depression: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials

Geschlechtsunterschiede bei der Akupunkturbehandlung von Patienten mit Depressionen

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