Schizophrene Psychosen im Kindesalter

Remschmidt, Helmut

doi:10.1007/978-3-642-71817-5_4

Cited by 8 publications

(3 citation statements)

References 52 publications

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“…The two conditions are not more commonly observed together than would be expected by chance (Volkmar and Cohen, 1991). Our own studies show that up to the age of 12 years, all psychotic states are rare conditions, but after the 13 th year of life, there is a remarkable increase of schizophrenia (Remschmidt, 1988;Remschmidt et al, 1994). The disorder can be diagnosed according by the same criteria as used for adults according to the current classification systems ICD-10 and DSM-IV.…”

Section: Introductionmentioning

confidence: 98%

Early-onset schizophrenia as a progressive-deteriorating developmental disorder: evidence from child psychiatry

Remschmidt

2002

Journal of Neural Transmission

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The developmental perspective as reflected by investigations of childhood and early-onset schizophrenia has become a major research area during recent years and contributed much to the understanding of schizophrenia at all ages. This paper reviews clinical features, neurobiological and neuropsychological findings in childhood and adolescent onset schizophrenia including some results of studies of the author on age at onset, premorbid symptoms, treatment and course. Childhood-onset schizophrenia is a rare disorder with a prevalence of one child in 10,000 before the age of 12 and a remarkable increase around puberty and early adolescence. Developmental events and precursors of schizophrenia cover a wide range of dysfunctions and disturbances including elevated rates of soft neurological signs and birth complications, slow habituation and high baseline autonomic activity, high rate of developmental disorders of speech and/or language and overall and specific cognitive deficits. Brain morphological studies and intelligence testing as well as investigations of the course provide evidence of deterioration. Therefore, early-onset schizophrenia can be understood as a progressive-deteriorating developmental disorder.

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Section: Introductionmentioning

confidence: 98%

Early-onset schizophrenia as a progressive-deteriorating developmental disorder: evidence from child psychiatry

Remschmidt

2002

Journal of Neural Transmission

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“…It is clear that with such low incidence rates, general population surveys might have a limited value. Early studies were hampered by not only the varied presentation of COS, but variable diagnostic criteria [ 21 ]. Clinical surveys have limitations—notably, sampling bias and non-standardised diagnosis.…”

Section: Discussionmentioning

confidence: 99%

National record-linkage study of hospital admissions for schizophrenia in childhood and adolescence in England

Seminog

Hoang

Goldacre

et al. 2021

Eur Child Adolesc Psychiatry

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Background There is a lack of information on changes in hospital admission rates for childhood-onset schizophrenia (COS), or on patient characteristics, to inform clinical research and health service provision. Aims To report age- and sex-specific incidence rates of hospital admissions and day patient care for schizophrenia (ICD-10 F20) and non-affective psychosis (ICD-10 F20-29), by year of occurrence and age, in childhood and adolescence. Methods Population-based study using person-linked data for England (available 2001–2016); time-periods in single years and 4-year groups. Results Hospitalised incidence for schizophrenia increased with increasing age, from 0.03 (95% confidence interval (CI) 0.02–0.05) and 0.01 (0–0.01) per 100,000 in, respectively, males and females aged 5–12 years, to 3.67 (3.44–3.91) in males and 1.58 (1.43–1.75) in females aged 13–17 years. There was no gender difference in hospitalised incidence rates in children aged 5–12, but in 13–17 years old, there was a male excess. Rates for schizophrenia were stable over time in 5–12 years old. In ages 13–17, rates for schizophrenia decreased between 2001–2004 and 2013–2016 in males, from 6.65 (6.04–7.31) down to 1.40 (1.13–1.73), and in females from 2.42 (2.05–2.83) to 1.18 (0.92–1.48). The hospitalisation rates for schizophrenia and non-affective psychosis, combined, in 13–17 years old decreased in males from 14.20 (13.30–15.14) in 2001–2004 to 10.77 (9.97–11.60) in 2013–2016, but increased in females from 7.49 (6.83–8.20) to 10.16 (9.38–11.00). Conclusions The study confirms that childhood-onset schizophrenia is extremely rare, with only 32 cases identified over a 15-year period in the whole of England. The incidence of schizophrenia and non-affective psychosis increased substantially in adolescence; however, the marked reduction in the proportion of those diagnosed with schizophrenia in this age group suggests a possible change in diagnostic practice.

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“…Lebensjahr einen markanten Häu-figkeitsanstieg aufweist [16]. Auch die Geschlechterrelation (57% männliche und 43% weibliche Patienten) entspricht in unserer Schizophreniestichprobe den publizierten Daten kinder-und jugendpsychiatrischer Einrichtungen, ebenso die umgekehrte Geschlechterrelation bei den affektiven Störungen sowie die ausgesprochene Dominanz des männlichen Geschlechts bei den Störungen des Sozialverhaltens.…”

Section: Soziodemografische Und Klinische Datenunclassified

Schizophrenia in children and adolescents

2004

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This paper analyses sociodemographic, clinical, and descriptive data and data concerning cooperation in a sample of 305 consecutively treated inpatients with schizophrenia. The data of this group were compared with those from two other diagnostic groups (affective disorders, n=318; conduct disorders, n=982) who were treated as inpatients at the same time. Schizophrenic patients were significantly older at admittance (mean 17.6 years) than patients in the other two diagnostic groups (affective disorders 15.9 years, conduct disorders 13.1 years). On average, the inpatient treatment stay was longer in schizophrenic patients (by approximately 1 month) than in both of the other groups, and dropout was less frequent (5% vs 9% in affective disorders and 11% in conduct disorders). The treatment of the three patient groups was based on a multidimensional program following a model including five components: individual psychotherapy, family-centered measures, functional therapies, sociotherapeutic measures, and medication.

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Schizophrene Psychosen im Kindesalter

Cited by 8 publications

References 52 publications

Early-onset schizophrenia as a progressive-deteriorating developmental disorder: evidence from child psychiatry

Early-onset schizophrenia as a progressive-deteriorating developmental disorder: evidence from child psychiatry

National record-linkage study of hospital admissions for schizophrenia in childhood and adolescence in England

Schizophrenia in children and adolescents

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