Schistosoma mansoni: Parasitology and immunology of baboons vaccinated with irradiated cryopreserved schistosomula

Why the radiation-attenuated cercarial immunization studies failed to guide the road for an effective schistosomiasis vaccine: A review

“…At 8 weeks after challenge, the egg count/mouse and per female worm was similar in immunized and control mice suggesting that the RA vaccine-mediated decrease in worm egg load is only transient [68] . In studies complete regarding egg sampling, significant reduction in fecundity of challenge worms was not observed in baboons immunized with S. haematobium [66] , or S. mansoni [69] RA cryopreserved schistosomula.…”