Schistosoma mansoni infection and related knowledge among schoolchildren in an endemic area of Minas Gerais, Brazil, prior to educational actions

Cabello, Rocío Karina Saavedra Acero; Beck, Lílian; Massara, Crístiano Lara; Murta, Felipe; Guimarães, Ricardo José de Paula Souza e; Pieri, Otávio Sarmento; Schall, Virgínia Torres; Favre, Tereza Cristina

doi:10.1016/j.actatropica.2016.09.015

Cited by 13 publications

(15 citation statements)

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“…The Téofilo Otoni microregion (Minas Gerais state) conferred the highest number of reported cases per 100,000 inhabitants aged up to 19 years. Indeed, a study carried out in Malacacheta, a municipality located in Téofilo Otoni, highlighted the high prevalence of infection by S. mansoni in schoolchildren, mainly in boys aged ≥11 years living in rural areas [ 39 ]. Similarly, a significant proportion of reported cases was found among boys aged 10–19 years.…”

Section: Discussionmentioning

confidence: 99%

Neglected tropical diseases in Brazilian children and adolescents: data analysis from 2009 to 2013

et al. 2017

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BackgroundNeglected tropical diseases (NTDs) prevail in conditions of poverty and contribute to the maintenance of social inequality. Out of the NTDs prioritized by the Brazilian Ministry of Health, four parasitic infections require mandatory notification: acute Chagas disease, leishmaniasis, malaria, and schistosomiasis. Data on the behaviour of these NTDs in the young population are currently limited. This study seeks to analyse the epidemiological aspects of these parasitic infections in children and adolescents in Brazil.MethodsA retrospective exploratory ecological study was conducted. A spatial analysis of the cases reported between 2009 and 2013 in individuals aged between 0 and 19 years that were notified through the Health Notification Aggravation Information System (SINAN) was performed.ResultsIn total, 64,567 cases of cutaneous and visceral leishmaniasis, malaria, schistosomiasis, and acute Chagas disease were recorded in the SINAN database, representing a rate of 20.15 cases per 100,000 inhabitants. The average age of the cases was 12.2 years and 62.32% were male. Four hundred and three deaths related to these obligatorily reported parasites were recorded, indicating a case fatality rate of 0.62%. Visceral leishmaniasis and acute Chagas disease had the highest rates of lethality. A heterogeneous spatial distribution of the studied parasites was observed.ConclusionsThe number of cases and the lethality rate described in this study show that these diseases still represent a serious problem for public health in Brazil. This points to the need to encourage new research and the reformulation of social, economic, and public health policies aimed at ensuring better health and living conditions for all individuals, especially those among the populations considered vulnerable, as is the case of the young.Electronic supplementary materialThe online version of this article (10.1186/s40249-017-0369-0) contains supplementary material, which is available to authorized users.

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Section: Discussionmentioning

confidence: 99%

Neglected tropical diseases in Brazilian children and adolescents: data analysis from 2009 to 2013

et al. 2017

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“…Essas regiões se situam principalmente próximas as zonas equatoriais e tropicais, com condições climáticas e de habitats (açudes e lagos) que favorecem a proliferação do vetor intermediário (B. glabrata). Outro fato relacionado é a baixa escolaridade formal média dos indivíduos que vivem nessas regiões, o que torna ineficientes políticas de prevenção e higienização contra os vetores e as atitudes de riscos para doença (BROOKER et al, 2006;CABELLO et al, 2016;DISCH et al, 2002;FONSECA et al, 2014;GAZZINELLI et al, 2006;KATZ, 2008;KLOETZEL, 1989;LIMA E COSTA et al 1985;PEREIRA et al, 2010;SAVIOLI et al, 2017;SCHOLTE et al, 2014;SLEIGH et al, 1985;UCHOA et al, 2000). O Semiárido brasileiro é uma área de risco, pois apresenta variáveis favoráveis à disseminação da esquistossomose, seja espacialmente (presença de açudes e lagos), seja em relação ao índice de desenvolvimento humano municipal (< 0,30 em média).…”

Section: Introductionunclassified

“…Mundialmente, em torno de 14% dos indivíduos diagnosticados falecem, somente no semiárido brasileiro, esse número chega a 22% (MINISTÉRIO DA SAÚDE, 2018; OMS, 2018), causa mortis associada a desnutrição e desidratação (BROOKER et al 2006;CABELLO et al 2016;GAZZINELLI et al 2016;KLOETZEL et al 1989;SAVIOLI et al 2017;SLEIGH et al 1985). O diagnóstico da esquistossomose é realizado basicamente pela coproscopia quali-quantitativa (Hoffman e Kato-Katz), por hemogramas (eosinofilia, leucopenia, anemia, plaquetopenia, TGO, TGP e fosfatase alcalina), pela ultrasonografia (patognomônico a fibrose e espessamento periportal, hipertrofia do lobo hepático esquerdo e aumento do calibre da mesentérica superior) e por biopsia retal (GRYSEELS, 2004;UTZINGER et al 2015).…”

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Pré-diagnóstico da esquistossomose no semiárido: régua antropométrica e aplicativo colaborativo

et al. 2019

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A esquistossomose é uma doença tropical negligenciada pertencente ao grupo das infecções helmínticas, causada pelo parasita do gênero Schistosoma, que tem afetado pessoas em todo o mundo. No Brasil, cem milhões de casos foram registrados nos últimos trinta e sete anos. Os objetivos desta dissertação foram detectar uma zona pré-diagnóstica para esquistossomose na relação entre o índice de massa corporal e a circunferência abdominal de indivíduos suspeitos de terem essa doença e propor uma ferramenta e um aplicativo colaborativo que terá também um uso educacional. Os procedimentos metodológicos seguiram seis passos: i) a alimentação do banco de dados; ii) a modelagem estatística; iii) a sistematização da árvore de decisão diagnóstica pelas variáveis; iv) a construção de uma régua antropométrica e de um aplicativo colaborativo; v) a aplicação das ferramentas construídas; e, vi) a análise quali-quantitativa. As ferramentas construídas participaram de maneira eficiente para o pré-diagnóstico da esquistossomose, com a redução da passagem de pacientes da fase aguda para fases crônica e pós-crônica, contribuindo com o paciente, no sentido de qualidade e no tempo do tratamento, e com a redução de gastos pelo sistema público de saúde. O mesmo foi relatado para as atividades de ensino e aprendizagem, a utilização das ferramentas por docentes e agentes de saúde em seus ambientes de laboro pôde apresentar de forma lúdica a aplicação da árvore de decisão para o pré-diagnóstico da doença em questão, a resultar na apropriação do conteúdo e da práxis pelo aprendiz.

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“…Urban schistosomiasis caused by S . mansoni has been reported elsewhere, including Brazil [ 37 ], Côte d’Ivoire [ 38 ] and Tanzania [ 39 ], but most of these studies did not include preschool-aged children. However, intense transmission of S .…”

Section: Discussionmentioning

confidence: 99%

Schistosoma, other helminth infections, and associated risk factors in preschool-aged children in urban Tanzania

et al. 2017

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BackgroundDespite the high prevalence of helminth infections among preschool-aged children, control programs in sub-Saharan countries primarily focus on school-aged populations. We assessed the prevalence of helminth infections and determined risk factors for infection among preschool-aged children in the urban setting of Dar es Salaam, Tanzania.MethodologyStarting in October 2015, we conducted a 12-month prospective study among tuberculosis (TB)-exposed children under the age of 5 years and unexposed controls from neighboring households. At the time of recruitment, we collected medical histories, assessed development and cognitive functions, and performed medical examinations. We performed full blood cell counts and screened for HIV and malaria. Point-of-care circulating cathodic antigen (POC-CCA), urine filtration, Kato-Katz, FLOTAC, and Baermann tests were employed to detect helminth infections in urine and stool. Helminth infections were stratified for Schistosoma and other helminths to identify risk factors, using logistic regression.Principal findingsWe included 310 children with a median age of 26 months (inter quartile range 17–42 months) in the study. Among these, 189 were TB-exposed and 121 TB-unexposed. Two thirds of the children were anemic (hemoglobin level <11 g/dl) and the HIV prevalence was 1.3%. Schistosoma spp. was the predominant helminth species (15.8%; 95% confidence interval [CI] 12.1–20.3%). Other helminth infections were less frequent (9.0%, 95% CI 6.3–12.8%). Poor hygiene, use of household water sources, and TB-exposure were not associated with helminth infection. Development and cognitive scores did not significantly differ in helminth-infected and uninfected peers, but hemoglobin levels were significantly lower in helminth-infected children (10.1 g/dl vs. 10.4 g/dl, p = 0.027).Conclusions/significanceIn Dar es Salaam, a city with more than 4 million inhabitants, the prevalence of Schistosoma spp. infection among preschool-aged children was unexpectedly high. Setting-specific interventions that target preschool-aged children and urban settlements should be considered to reduce the transmission of Schistosoma and other helminth infections and to improve children’s health.

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Schistosoma mansoni infection and related knowledge among schoolchildren in an endemic area of Minas Gerais, Brazil, prior to educational actions

Cited by 13 publications

References 24 publications

Neglected tropical diseases in Brazilian children and adolescents: data analysis from 2009 to 2013

Neglected tropical diseases in Brazilian children and adolescents: data analysis from 2009 to 2013

Pré-diagnóstico da esquistossomose no semiárido: régua antropométrica e aplicativo colaborativo

Schistosoma, other helminth infections, and associated risk factors in preschool-aged children in urban Tanzania

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