Schiff Bases of Hydroxyacetophenones and their Copper(II) and Nickel(II) Complexes: Synthesis, Antioxidant Activity and Theoretical Study

Significant Aspects of Heterocyclic Schiff Bases and Their Metal Complexes

“…Hence, the structural diversities and inherent chemical properties of HSB-based molecules provide scopes for numerous utilities in different segments. Without limiting their applications in the above-mentioned zones, these molecules too exhibit some foremost activities in the field of antimalarial, antiviral, anti-inflammatory, antioxidant, and anti-obesity that have been documented in the literature [16,[64][65][66]. In the contemporary period, the pharmacological applications of HSB-related compounds have excellent potential and are widely used within the pharmaceutical sector.…”

Review Article on Metal Complexes derived from 2’-hydroxyacetophenone based Schiff Base

“…Mixed ligand complex of Co 2+ ion complexes with 5-chloro-2-hydroxyacetophenone N(4)methylthiosemicarbazone and heterocyclic base (Pyridine, 2,2'-bipyridine, β-picoline,1,10phenanthroline, α-picoline) 13 and complexes of Schiff base (o-hydroxyacetophenone and L-cystein with Ethylenediamine) have been studied for antioxidant activities 16 . Co 2+ and Ni 2+ ions Schiff base complexes with tryptamine and 5-methoxy-2-hydroxyacetophenone, 5-methyl-2hydroxyacetophenone and 2-hydroxyacetophenone were also formed to check their anti-oxidant properties 31 .…”

“…Co 2+ and Ni 2+ ions Schiff base complexes with tryptamine and 5-methoxy-2-hydroxyacetophenone, 5-methyl-2-hydroxyacetophenone and 2-hydroxy -acetophenone were formed 31 . 2+ and Fe 2+ ions were formed by 2-hydroxyacetophenone and tyrosine as first ligand with 4-diamethylaminobenzaldehyde and 2,4dinitrophenylhydrazine as second ligand 46 .…”