Schiff base metal complexes as a versatile catalyst: A review

Juyal, Vijay Kumar; Pathak, Abhishek; Panwar, Mohit; Thakuri, Shweta Chand; Prakash, Om; Agrwal, Akansha; Nand, Viveka

doi:10.1016/j.jorganchem.2023.122825

Cited by 42 publications

(14 citation statements)

References 141 publications

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“…A few azo-azomethine metal complexes have been used extensively in technology due to their photophysical and energy-transfer capabilities. Because of their stability, electroactivity, thermochromism, and photochromism, Schiff base compounds make excellent intermediates for a variety of uses. − Numerous reviews revealed that the metallo-organic chemistry of such compounds significantly affected how they acted biologically, highlighting the role played by metals as catalysts in a variety of biological processes. − Higher electronegative atoms’ connected bonding orbitals and electrons can be adsorbed on metal surfaces due to their electrons’ C=N faction planarity. This substance contributes significantly to the development of inorganic biochemistry and is used as a substrate in ring closure, cycloaddition, and replacement reactions to produce a variety of biologically active compounds. − …”

Section: Introductionmentioning

confidence: 99%

Synthesis and Spectroscopic Characterization of Schiff Base Metal Complexes, Biological Activity, and Molecular Docking Studies

Venkatesh,

Vennila,

Kaya

et al. 2024

ACS Omega

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New cobalt(II), copper(II), and zinc(II) Schiff metal complexes were synthesized by the condensation reaction of 4-nitrobenzene-1,2-diamine with 3−4-(diethylamino)-2-hydroxybenzaldehyde. Fourier transform infrared, nuclear magnetic resonance, ultraviolet−visible, electron paramagnetic resonance, and high-resolution electrospray ionization mass spectrometry and powder X-ray diffraction were used to characterize the synthesized H 2 L and its metal complexes. Conductance measurements, magnetic moment estimation, and metal estimation have all been determined and discussed. The electrochemical properties of the synthesized compounds have been determined and discussed using cyclic voltammetry. The molecular structures of H 2 L and its metal complexes have been optimized using the B3LYP functional and the 6-31G (d,p) basis set, and their parameters have been discussed. The quantum chemical properties of these synthesized compounds have been predicted through charge distribution and molecular orbital analysis. The biological properties of the synthesized compounds' antioxidant, antifungal, and antibacterial activity have been studied and discussed. Furthermore, H 2 L and its complexes have been docked with HER2associated target proteins in breast cancer.

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Section: Introductionmentioning

confidence: 99%

Synthesis and Spectroscopic Characterization of Schiff Base Metal Complexes, Biological Activity, and Molecular Docking Studies

Venkatesh,

Vennila,

Kaya

et al. 2024

ACS Omega

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“…The organic ligands containing the Schiff base moieties have been widely used in organometallic, transition metal and medicinal chemistry. [1] Many metal ions are capable of forming metal complexes by coordinating with Schiff base ligands. These metal complexes, which exhibit a wide variety of structures due to sigma donor groups for the metal cation and π acceptor atoms on the nitrogen (> C=NÀ ) atom in the imine group are widely investigated.…”

Section: Introductionmentioning

confidence: 99%

“…For this reason, the zinc complexes with the Schiff base complexes containing N-, O-, S-donor atoms as well as many different ligands that do not contain Schiff bases have been synthesized, and researchers continue to show great interest in the designes, syntheses and characterizations of new zinc complexes. [1] In this context, we synthesized the Schiff base ligands and their zinc (II) complexes. The synthesized ligands and complexes are characterized by 1 H, 13 C NMR and FT-IR spectrocopies and single crystal X-ray diffraction technique.…”

Section: Introductionmentioning

confidence: 99%

“…[1] In this context, we synthesized the Schiff base ligands and their zinc (II) complexes. The synthesized ligands and complexes are characterized by 1 H, 13 C NMR and FT-IR spectrocopies and single crystal X-ray diffraction technique. The experimental results are supported by the computational results obtained with DFT/ B3LYPand HF methods at different basis sets.…”

Section: Introductionmentioning

confidence: 99%

“…The organic ligands containing the Schiff base moieties have been widely used in organometallic, transition metal and medicinal chemistry [1] . Many metal ions are capable of forming metal complexes by coordinating with Schiff base ligands.…”

Section: Introductionmentioning

confidence: 99%

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Syntheses, Crystal Structure and Theoretical Properties of Schiff Bases Obtained from Isoniazid and Pyridine‐2‐, 3‐, 4‐Carboxaldehyde and Their Zinc(II) Complexes

Aydoğdu,

Uğurlu,

Necefoğlu

et al. 2024

ChemistrySelect

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The series of Schiff base ligands, N’‐(pyridine‐2‐ylmethylene)isonicotinohydrazide (I), N’‐(pyridine‐3‐ylmethylene)isonicotinohydrazide (II) and N’‐(pyridine‐4‐ylmethylene)isonicotinohydrazide (III), and the Zn(II) complexes of the ligands (I and II), [N’‐(pyridine‐2‐ylmethylene)isonicotinohydrazide]‐trichlorozincoate (IV) and [N’‐(Pyridin‐3‐ylmethylene) isonicotinohydrazide] trichlorozincoate (V) have been newly synthesized and their structures have been characterized by 1H, 13C NMR and FT‐IR spectroscopies, elemental analysis and single crystal X‐ray diffraction technique. The Hirshfeld surface analyses have been confirmed the importance of H‐atom contacts in establishing the packings. The ground state equilibrium geometries of the synthesized compounds are optimized at DFT/B3LYP/6‐311++G (d, p) and HF/6‐311++G (d, p) levels of theory (for the ligands) and B3LYP/GENECP method is used as the mixed basis sets of LANL2DZ (for Zn) and 6–311G (for other atoms) in the gas‐phase. The structural parameters obtained from the theoretical studies of the compounds are compared with their experimental ones. Their linear and nonlinear optical (NLO) properties are also calculated by the same methods. In the ground state, the energy band gaps (Eg) of the Schiff bases (I, II and III) have been calculated as 4.38 eV, 4.36 eV and 4.46 eV (at B3LYP) and 9.94 eV, 9.81 eV and 10.20 eV (at HF), respectively.

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Complexation behavior of copper and zinc divalent ions towards diisatin malonyl dihydrazone ligand with biological and catalytic assessments

Adam,

Alghanim,

Abualreish

et al. 2024

Applied Organom Chemis

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According to the interesting reactivity of arylhydrazones in coordination chemistry and biological assays, malonyl dihydrazone ligand of diisatin derivative (H2Lm) was reacted with Cu2+ and Zn2+ ions forming two complexes of dinuclear homoleptic mode (CuLm and ZnLm, respectively). Demonstration of their chemical structures was confirmed through various spectroscopic ways alongside the elemental analyses (EA), conductivity measurements, and magnetic characteristics.Their bio‐performance was recorded based on their inhibited potential of the growing ability of some common bacteria, fungi, and human cancer/normal cell lines. The biological studies appointed the role and job of M2+ ion = Cu2+ or Zn2+ in its chelated MLm complex to perform the bio‐reactivity over the free ligand, H2Lm. Moreover, their interacted modes with ctDNA (i.e., calf thymus DNA) were examined via the viscometry and spectrophotometric titration. Because the two chelates (CuLm and ZnLm) represented an attractive job for the inhibited action against the current microorganisms and the human cancer/normal strains' growth over the free H2Lm ligand, CuLm and ZnLm complexes displayed a distinguished interaction with ctDNA more than that of their uncoordinated H2Lm ligand. From the values of binding constant (Kb) and Gibb's free energy ( ), CuLm assigned more bio‐action within ctDNA more than ZnLm H2Lm ligand, referring to the role of Cu2+ ion with more electronegativity to enhance the reactivity of CuLm over their free H2Lm ligand and ZnLm.The catalytic behavior of CuLm and ZnLm was given within the epoxidation of 1,2‐cyclohexene (an example of unsaturated hydrocarbons) homogeneously using hydrogen peroxide (the oxidant). Their catalytic action was optimized through various temperatures, solvents, time, and type of M2+ ion in the catalyst.

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Schiff base metal complexes as a versatile catalyst: A review

Cited by 42 publications

References 141 publications

Synthesis and Spectroscopic Characterization of Schiff Base Metal Complexes, Biological Activity, and Molecular Docking Studies

Synthesis and Spectroscopic Characterization of Schiff Base Metal Complexes, Biological Activity, and Molecular Docking Studies

Syntheses, Crystal Structure and Theoretical Properties of Schiff Bases Obtained from Isoniazid and Pyridine‐2‐, 3‐, 4‐Carboxaldehyde and Their Zinc(II) Complexes

Complexation behavior of copper and zinc divalent ions towards diisatin malonyl dihydrazone ligand with biological and catalytic assessments

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