Scheme optimization of acupoints compatibility and influence factors of the effect

Ha, Lijuan; Liu, Xiaona; Liu, Yanze; Zhi, Mujun; Jiang, Hailin; Zhao, Jun; Wang, Yiming; Xu, Xiaoru; Guo, Lei; Cao, Jiazhen; Chen, Liyuan; Yuan, Yue; Li, Tie; Wang, Fuchun

doi:10.1097/md.0000000000027883

Cited by 3 publications

(3 citation statements)

References 19 publications

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“…Based on the results of our review, we found that the most used acupoints for treating CRI are GV20, SP6, and HT7. GV20-SP6-HT7 is also the most used combination of main acupoints for treating insomnia ( 72 ). Studies have shown that acupuncture at GV20 can significantly improve the expression levels of clock genes and amino acid neurotransmitters in the brain tissue of rats with insomnia, thus improving sleep ( 73 ).…”

Section: Discussionmentioning

confidence: 99%

Acupuncture and moxibustion in patients with cancer-related insomnia: A systematic review and network meta-analysis

Dong

et al. 2023

Front. Psychiatry

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ObjectivesCancer-related insomnia (CRI) is one of the most common and serious symptoms in patients with cancer. Acupuncture and moxibustion have been widely applied in the treatment of CRI. Nevertheless, the comparative efficacy and safety of different acupuncture and moxibustion techniques remain unclear. This study aimed to evaluate and compare the efficacy and safety of different acupuncture and moxibustion techniques in the treatment of CRI.MethodsEight medical databases were comprehensively searched for relevant randomized controlled trials (RCTs) as of June 2022. Two independent reviewers assessed the risk of bias and conducted the research selection, data extraction, and quality assessment of the included RCTs. A network meta-analysis (NMA) was performed using frequency models, combining all available direct and indirect evidence from RCTs. The Pittsburgh Sleep Quality Index (PSQI) was set as the primary outcome, and adverse events and effective rates were set as the secondary outcomes. The efficacy rate was calculated as the ratio of patients with insomnia symptom relief to the total number of patients.ResultsThirty-one RCTs with 3,046 participants were included, including 16 acupuncture- and moxibustion-related therapies. Transcutaneous electrical acupoint stimulation [surface under the cumulative ranking curve (SUCRA) 85.7%] and acupuncture and moxibustion (SUCRA 79.1%) were more effective than Western medicine, routine care, and placebo-sham acupuncture. Furthermore, Western medicine showed significantly better effects than placebo-sham acupuncture. In the NMA, the acupuncture and moxibustion treatments with the best therapeutic effects for CRI were transcutaneous electrical acupoint stimulation (SUCRA 85.7%), acupuncture and moxibustion (SUCRA 79.1%), auricular acupuncture (SUCRA 62.9%), routine care combined with intradermal needling (SUCRA 55.0%), and intradermal needling alone (SUCRA 53.3%). No serious acupuncture- or moxibustion-related adverse events were reported in the included studies.ConclusionAcupuncture and moxibustion are effective and relatively safe in treating CRI. The relatively conservative recommended order of acupuncture- and moxibustion-related therapies for CRI is as follows: transcutaneous electrical acupoint stimulation, acupuncture and moxibustion, and auricular acupuncture. However, the methodological quality of the included studies was generally poor, and further high-quality RCTs are needed to strengthen the evidence base.

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Section: Discussionmentioning

confidence: 99%

Acupuncture and moxibustion in patients with cancer-related insomnia: A systematic review and network meta-analysis

Dong

et al. 2023

Front. Psychiatry

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“…Acupuncturists mostly use their experience and the patient’s schedule to pre-determine the treatment course, with a long refractory and chronic disease duration when treating diseases, and acute conditions may need a shorter course of acupuncture. 36 OAB is a chronic disease mostly suffered by middle-aged and elderly females, and a longer treatment cycle should be developed according to TCM ideas. Hargreaves et al 37 considered that acupuncture for OAB was usually 1 session per week to achieve a course of 4–12 sessions, and acupuncture also has a continual therapeutic effect and may be more clinically relevant for long-term efficacy measurement.…”

Section: Discussionmentioning

confidence: 99%

Acupuncture for Women with Overactive Bladder: Perspective of Traditional Chinese Medicine and Related Mechanism

Wang¹,

Lei²

2023

IJGM

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Purpose Overactive bladder (OAB) syndrome is one of the most common diseases in urology and affects quality of life. Although the current treatment for OAB is based on oral medications, there are limitations and many patients have difficulty accepting drug-induced adverse effects. This review aimed to analyze the efficacy of acupuncture and its related mechanisms and provide a preliminary therapeutic regimen. Methods Two authors independently searched PubMed, Embase, and Cochrane Library up to April 2022. They searched related English literature and extracted the data under a standard form based on the search strategy. Clinical trials which included OAB women with the treatment of acupuncture were included. Common acupuncture alone without other pharmacotherapy, external treatments was in the treatment group. The control interventions may include any active treatments, sham placebo, or no establishment of a control group. Outcomes included 3-day or 24-hour voiding diary, overactive bladder symptom score, etc. The Cochrane risk of bias tool was also used to assess the methodological quality of the randomized controlled trials (RCTs). Results We analyzed five RCTs and one comparative study on acupuncture for OAB to review and discuss the acupoint location, treatment course, and retention time based on clinical evidence and treatment ideas in traditional Chinese medicine. Additionally, we used the available evidence to reveal and discuss the acupuncture mechanisms for OAB. Acupuncture may regulate bladder function by inhibiting C-fibers, modulating nerve growth factors and reducing spontaneous contractions of the detrusor muscle. Conclusion Combined with the available evidence, the combination of local acupoints and distal acupoints should be necessary to consider, especially the lumbosacral acupoints, the small abdomen acupoints and the lower limb acupoints. Among them, acupuncture at SP4, CV4 and KI3 are strongly recommended. The treatment course of acupuncture should be no less than 4 weeks and maintain the frequency of acupuncture no less than once a week. The duration of each session should be no less than 20 minutes. In addition, investigations remain necessary to verify acupuncture’s efficacy and precise mechanism for OAB treatment in further exploration.

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“…HT7 is the international code of Shenmen , which is the acupoint on the Shaoyin Heart Channel of Hand (手少阴心经). In TCM theory, it has the function of promoting digestion, helping sleep and regulating visceral nerves ( 76 , 77 ). Based on TCM theory, the pathogenesis of ASD is related to the abnormal function of the heart, liver, spleen, and kidney.…”

Section: Clinical Trialsmentioning

confidence: 99%

Research status and prospects of acupuncture for autism spectrum disorders

et al. 2023

Front. Psychiatry

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Autism spectrum disorder (ASD) is a neurodevelopmental disorder and has a predilection for children. Its symptoms, such as lifelong social communication deficits and repetitive sensory-motor behaviors, put a huge burden on the patient’s family and society. Currently, there is no cure for ASD, and some medications that can improve its symptoms are often accompanied by adverse effects. Among many complementary and alternative medicine (CAM) therapies, acupuncture has shown promising application potential, but after years of practice, it has not been recognized as the preferred CAM therapy for ASD. Therefore, we analyzed and discussed the clinical study reports of acupuncture in the treatment of ASD in the past 15 years from the aspects of study subjects, group setting, intervention modalities, acupoint selection, outcome evaluation, and safety. The data accumulated at present are not sufficient to support the clinical effectiveness of acupuncture in ASD and to justify its use in clinical practice. They provide, however, initial evidence of possible effectiveness and encourage further investigation in order to reach firm conclusions. Based on a comprehensive analysis, we believed that following the Standards for Reporting Interventions in Clinical Trials of Acupuncture (STRICTA) and Consolidated Standards of Reporting Trials (CONSORT), screening the optimal combination of acupoints applying a rigorous scientific study design, and performing the related functional experiments may be the effective way to convincingly test the hypothesis that acupuncture may be beneficial in ASD patients. The significance of this review is to provide a reference for researchers to carry out high-quality clinical trials of acupuncture in the treatment of ASD from the perspective of the combination of modern medicine and traditional Chinese medicine.

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Scheme optimization of acupoints compatibility and influence factors of the effect

Cited by 3 publications

References 19 publications

Acupuncture and moxibustion in patients with cancer-related insomnia: A systematic review and network meta-analysis

Acupuncture and moxibustion in patients with cancer-related insomnia: A systematic review and network meta-analysis

Acupuncture for Women with Overactive Bladder: Perspective of Traditional Chinese Medicine and Related Mechanism

Research status and prospects of acupuncture for autism spectrum disorders

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