Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present and Lifetime Version

Kaufman, John A.; Birmaher, Boris; Brent, David; Rao, Uma; Flynn, Cynthia; Moreci, Paula; Williamson, Douglas E.; Ryan, Neal D.

doi:10.1037/t03988-000

Cited by 347 publications

(382 citation statements)

References 27 publications

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“…All participants were recruited from the community by newspaper advertisement and flyer distribution in the context of an ongoing study of adolescent tobacco use. All subjects were free of medical and psychiatric illness and substance abuse or dependence disorders, other than nicotine dependence, as determined by physical exam and structured clinical interview using the Schedule for Affective Disorders and Schizophrenia for School Aged Children (Kaufman et al, 1996) performed at initial screening. Detailed drug use history was obtained using the Comprehensive Addiction Severity Index for Adolescents (Meyers et al, 1995).…”

Section: Participantsmentioning

confidence: 99%

Visuospatial Memory Deficits Emerging During Nicotine Withdrawal in Adolescents with Prenatal Exposure to Active Maternal Smoking

Jacobsen

Slotkin

Westerveld

et al. 2005

Neuropsychopharmacol

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Active maternal smoking during pregnancy elevates the risk of cognitive deficits and tobacco smoking among offspring. Preclinical work has shown that combined prenatal and adolescent exposure to nicotine produces more pronounced hippocampal changes and greater deficits in cholinergic activity upon nicotine withdrawal than does prenatal or adolescent exposure to nicotine alone. Few prior studies have examined the potential modifying effects of gestational exposure to active maternal smoking on cognitive or brain functional response to tobacco smoking or nicotine withdrawal in adolescents. We examined visuospatial and verbal memory in 35 adolescent tobacco smokers with prenatal exposure to active maternal smoking and 26 adolescent tobacco smokers with no prenatal exposure to maternal smoking who were similar in age, educational attainment, general intelligence, and baseline plasma cotinine. Subjects were studied during ad libitum smoking and after 24 h of abstinence from smoking. A subset of subjects from each group also underwent functional magnetic resonance imaging while performing a visuospatial encoding and recognition task. Adolescent tobacco smokers with prenatal exposure experienced greater nicotine withdrawal-related deficits in immediate and delayed visuospatial memory relative to adolescent smokers with no prenatal exposure. Among adolescent smokers with prenatal exposure, nicotine withdrawal was associated with increased activation of left parahippocampal gyrus during early recognition testing of visuospatial stimuli and increased activation of bilateral hippocampus during delayed recognition testing of visuospatial stimuli. These findings extend prior preclinical work and suggest that, in human adolescent tobacco smokers, prenatal exposure to active maternal smoking is associated with alterations in medial temporal lobe function and concomitant deficits in visuospatial memory.

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Section: Participantsmentioning

confidence: 99%

Visuospatial Memory Deficits Emerging During Nicotine Withdrawal in Adolescents with Prenatal Exposure to Active Maternal Smoking

Jacobsen

Slotkin

Westerveld

et al. 2005

Neuropsychopharmacol

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“…The interview schedule used in this study was the Schedule for Affective Disorders and Schizophrenia for School-Age Children, Present and Lifetime Versions (K-SADS-PL ; Kaufman et al 1996). The K-SADS is a well-validated semi-structured research diagnostic interview for the assessment of all Axis-I psychiatric disorders in children and adolescents.…”

Section: Interview Instrumentmentioning

confidence: 99%

Cannabis use and childhood trauma interact additively to increase the risk of psychotic symptoms in adolescence

et al. 2009

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BackgroundAdolescent cannabis use has been shown in many studies to increase the risk of later psychosis. Childhood trauma is associated with both substance misuse and risk for psychosis. In this study our aim was to investigate whether there is a significant interaction between cannabis use and childhood trauma in increasing the risk for experiencing psychotic symptoms during adolescence.MethodPsychiatric interviews using the Schedule for Affective Disorders and Schizophrenia for School-Age Children (K-SADS) semi-structured instrument were carried out with 211 adolescents aged between 12 and 15 years and their parents as part of a population-based study. The interview enquired about early traumatic events, cannabis use and psychiatric symptoms in adolescence.ResultsIn separate analyses both cannabis use and childhood trauma were significantly associated with risk of experiencing psychotic symptoms. However, the presence of both childhood trauma and early cannabis use significantly increased the risk for psychotic symptoms beyond the risk posed by either risk factor alone, indicating that there was a greater than additive interaction between childhood trauma and cannabis use.ConclusionOur finding of a greater than additive interaction between childhood trauma and cannabis use may have implications for the identification of individuals at high risk of experiencing psychotic symptoms. For example, measures to actively discourage or intensively treat cannabis use in children and adolescents who have experienced abuse may help to prevent the development of psychosis in this vulnerable group. Our findings require replication in larger samples to confirm this interaction effect.

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“…The Diagnostic and Statistical Manual of Mental Disorders (DSM-IV-TR; APA, 2000) was used to provide an overall assessment of the severity of the child's behavior and emotional problems. In order to assist the clinicians in determining a reliable diagnosis for the children, the Kiddie Schedule for Affective Disorders and Schizophrenia for School-Aged Children (K-SADS-PL; Kaufman et al, 1997) was used. Besides the K-SADS-PL proven use with school age children, there also is evidence that it can be successfully applied to younger children.…”

mentioning

confidence: 99%

Evaluation of a University-Community Partnership to Provide Home-Based, Mental Health Services for Children from Families Living in Poverty

Fox

Mattek

Gresl

2012

Community Ment Health J

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Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present and Lifetime Version

Cited by 347 publications

References 27 publications

Visuospatial Memory Deficits Emerging During Nicotine Withdrawal in Adolescents with Prenatal Exposure to Active Maternal Smoking

Visuospatial Memory Deficits Emerging During Nicotine Withdrawal in Adolescents with Prenatal Exposure to Active Maternal Smoking

Cannabis use and childhood trauma interact additively to increase the risk of psychotic symptoms in adolescence

Evaluation of a University-Community Partnership to Provide Home-Based, Mental Health Services for Children from Families Living in Poverty

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