Scenario of Sepsis in Intensive Care Unit in a Tertiary Care Hospital

Abstract

Background: Sepsis has been defined as life-threatening organ dysfunction caused by dysregulated host response to infection. Sepsis is an important cause of mortality in intensive care unit worldwide. The study aims to identify the outcome of sepsis patient admitted at tertiary care hospital.Methods: This is a descriptive cross-sectional hospital based study on 76 adult patients admitted at intensive care unit of Nobel Medical College with diagnosis of sepsis with an objective of estimating mortality of sepsis and identifying associated symptoms with it. Baseline demographics, clinical and laboratory data were collected and analyzed. Results: Out of 76 patients with sepsis, mean age of the patients was 50.07±18.15 years. Majority of patients 31.6% with sepsis were above age groups >60 years. The most common symptoms among the patients were fever, which was seen in 69 (90.8%) patients. The most common source of infection in those patients was found to be unknown, which was seen in 36.8% of patients. While analyzing the outcome, it was noted that 25 patients with sepsis (32.9%) died during treatment.Conclusions: Sepsis is related with high mortality. Elderly patients are at more risk. Fever is the commonest presentation and source is not identified in majority of cases. Keywords: Intensive care unit; mortality; sepsis.

Is Dynamic Thiol/Disulfide Homeostasis Associated With the Prognosis of Geriatric Patients With Sepsis in the Intensive Care Unit

“…Sepsis is the leading cause of morbidity and mortality in patients hospitalized in the intensive care unit (ICU) (1). Older patients have a higher risk for mortality (2). In addition to the age factor in patients developing sepsis, determining other risk factors for patient mortality in ICU is imperative to sepsis prognosis (2,3).…”

“…Older patients have a higher risk for mortality (2). In addition to the age factor in patients developing sepsis, determining other risk factors for patient mortality in ICU is imperative to sepsis prognosis (2,3). Age, vital sign assessment, and other scoring systems are used for evaluation of the mortality data of patients hospitalized in ICU.…”