Scavenging neurotoxic aldehydes using lysine carbon dots

Abstract

Reactive aldehydes generated in cells and tissues are associated with adverse physiological effects. Dihydroxyphenylacetaldehyde (DOPAL), the biogenic aldehyde enzymatically produced from dopamine, is cytotoxic, generates reactive oxygen species, and triggers...

Modulating the optical properties of carbon dots by peptide condensates

“…The presence of doped nitrogen may lead to a redshift in the emission spectra, 28 further contributing to the broad fluorescence of the C-dots. 29 This coincides with the dependence of fluorescence on heteroatoms doped into the carbonaceous crystalline core of the C-dots. 35 The peak at 532.67 eV for the O1 provides further indication of the presence of phenol groups on the surface of the YCDots (Fig.…”

“…2f). The relatively wide size distribution is in line with a broad absorption and emission spectra, 29 in terms of C-dots properties. 34…”

“…2b), corresponding to the phenol group and the hydroxyl moiety within the phenol group, respectively. 30 These findings coincide with the structural memory property of C-dots., 29 for the phenol group originating in tyrosine is preserved on the YCDots surface in a conjugated form (Fig. 1).…”

“…C-dots are also characterized by ''structural memory'', the ability to present functional groups of their precursors on the surface of the carbon core. 29 C-dots may be classified based on their structure, atom content, and heterogeneity in the crystalline core made mainly out of carbon. 30 C-dots can also be synthesized from simple building blocks such as amino acids.…”

“…30 C-dots can also be synthesized from simple building blocks such as amino acids. 29,30 The functional group presented on the synthesized C-dots, originating from the amino acid, determines the quantum yield in correlation to hydrophobicity and volume. 31 Here, we synthesized C-dots from the aromatic amino acid tyrosine.…”