Abstract:The present study was to investigate the protective effect of Echinacea. purpurea (E. purpurea) extract, a natural scavenger of peroxynitrite (ONOO -), on the biomolecules injury induced by ONOO -in vitro. The results showed that E. purpurea extract could prevent the ONOO --mediated damage in tyrosine nitration, low density lipoprotein (LDL) oxidation and DNA strand breaks. The ONOO -scavenging ability of E. purpurea in the process of 3-nitrotyrosine (3-NT) formation exhibited dose-dependent manner. The result… Show more
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