Scavenging effect and antispasmodic activity of the essential oil of Cyclotrichium niveum

Çetinus, Şenay Akkuş; Göze, İsmihan; Saraç, Bülent; Vural, Nilüfer

doi:10.1016/j.fitote.2006.10.006

Cited by 19 publications

(13 citation statements)

References 14 publications

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“…All data selected were extracted from previous studies with similar results reported for the positive control butylhydroxytoluene (BHT) in order to reduce noise data as much as possible (Bozin, Mimica-Dukic, Samojlik, & Jovin, 2007;Burits & Bucar, 2000;Candan et al, 2003;Çetinus, Göze, Saraç, & Vural, 2007;Dermirci, Kos ßar, Dermirci, Dinç, & Bas ßer, 2007;Eminagaoglu et al, 2007;Fraternale, Giamperi, Bucchini, & Ricci, 2007;Gülüce et al, 2007;Jirovetz et al, 2006;Kartal et al, 2007;Mimica-Dukic, Bozin, Sokovic, & Simin, 2004;Özer et al, 2007;Ricci et al, 2005;Sacchetti et al, 2004;Sharififar, Moshafi, Mansouri, Khodashenas, & Khoshnoodi, 2007;Sökmen et al, 2004a;Sökmen et al, 2004b;Tepe et al, 2006;Tepe, Daferera, Sökmen, Polissiou, & Sökmen, 2004;Tepe et al, 2005;Tepe, Sökmen, Sökmen, Daferera, & Polissiou, 2005).…”

Section: Data Retrievalmentioning

confidence: 99%

Application of artificial neural networks to the prediction of the antioxidant activity of essential oils in two experimental in vitro models

Cortés-Cabrera

Prieto

2010

Food Chemistry

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Section: Data Retrievalmentioning

confidence: 99%

Application of artificial neural networks to the prediction of the antioxidant activity of essential oils in two experimental in vitro models

Cortés-Cabrera

Prieto

2010

Food Chemistry

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“…It has a distinct minty smell, and it is used in making soup and herbal teas, while it is also used as food flavoring in Turkey (8,9). Previous studies on the pharmacological roles of C. niveum revealed that the aqueous and ethanol extracts of this plant possessed in vitro antioxidant, antimicrobial and antispasmodic effects (9)(10)(11)(12). Moreover, a study suggested that C. niveum has an in vitro acetylcholinesterase (AChE) inhibitory effect (13).…”

Section: Introductionmentioning

confidence: 99%

Evaluation of the effects of Cyclotrichium niveum on brain acetylcholinesterase activity and oxidative stress in male rats orally exposed to lead acetate

Şahin

Özkaya

Uçkun

et al. 2019

Cell Mol Biol (Noisy-le-grand)

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Cyclotrichium niveum is an endemic plant for Turkey and it appears to have in vitro antioxidant and acetylcholinesterase inhibition properties. To the best of our knowledge, there has been no study on the in vivo effects of this plant. Therefore, the purpose of this study was to evaluate the effects of C. niveum on lead (Pb)-acetate-induced potential alterations in brain acetylcholinesterase activity, as well as oxidative stress in male rats. The rats were randomly assigned to control, Pb-acetate, C. niveum and Pb-acetate+ C. niveum groups. Pb-acetate was provided in drinking water (500 ppm), and C. niveum was administered via orogastric gavage (4 ml/kg) for 30 days. The acetylcholinesterase activity in the brain significantly decreased only in the Pb-acetate group. The malondialdehyde level significantly increased, and the reduced glutathione activity decreased in the Pb-acetate group. The reduced glutathione and glutathione-S-transferase activities of the C. niveum group were higher than the control group. No Pb was detected on a ppb level in the brain tissue of the control and C. niveum groups, while it was detected in the brains of the rats in the Pb-acetate and Pb-acetate+ C. niveum groups (185+8.98 ppb and 206+56.65 ppb, respectively). The data collected in this study suggested that C. niveum may reduce inhibition of brain AChE activity and oxidative stress against Pb-acetate-induced alterations in the brain of male rats.

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“…These synthetic substances may adversely affect health or cause certain diseases (Chan,1987;Barlow, 1990). In recent years for this reason, there is a growing interest in studies of natural additives as potential antioxidants as a natural additive for some plant extracts and essential oils is intended to use (Reynolds, 1996;Tepe et al, 2004;Akkuş-Çetinus et al, 2007;Tepe et al, 2016;Göze Saygın et al, 2018).…”

Section: Introductionmentioning

confidence: 99%

Scavenging Effect, Chemical Composition and Antispasmodic Activity of the Essential Oil of Origanum Onites L.

Korğalı

Saraç

2019

Turkish JAF Sci.Tech.

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Origanum onites L essential oil of antispasmodic activity, chemical composition and the radical scavenging were determined in vitro. GC-MS analysis that was been carried out upon the essential oil revealed 31 different composites which equal to 94.60% in which Carvacrol (49.01%), linalool (13.3%) were found as major components. Free radical scavenging capacities of the essential oil were measured by 2,2-diphenyl-1-pikrilhidrazil (DPPH) assay and via β-carotene linoleic acid experiment were determined. It showed IC50 value of Origanum onites essential oil was been identified as 430 mg/mL, the IC50 value for BHT was 19.8 mg/mL, the β-carotene linoleic acid assay also showed the 80% inhibition with the essential oil of Origanum onites.it showed very strong antioxidant activity. In addition, dose dependently (0.1, 0.5, 1.0 and 2 mg/mL) inhibits the contraction induced by, it was able to inhibit the rat ileum muscle by 2 mg/mL to 100%.

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Scavenging effect and antispasmodic activity of the essential oil of Cyclotrichium niveum

Cited by 19 publications

References 14 publications

Application of artificial neural networks to the prediction of the antioxidant activity of essential oils in two experimental in vitro models

Application of artificial neural networks to the prediction of the antioxidant activity of essential oils in two experimental in vitro models

Evaluation of the effects of Cyclotrichium niveum on brain acetylcholinesterase activity and oxidative stress in male rats orally exposed to lead acetate

Scavenging Effect, Chemical Composition and Antispasmodic Activity of the Essential Oil of Origanum Onites L.

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