Scanographic features of gastrointestinal stromal tumors

Velasco, S; Milin, Serge; Maurel, Christine; Richer, Jean‐Pierre; Sylvain, Christine; Hannequin, J; Tasu, J.P.

doi:10.1016/j.gcb.2008.07.011

Cited by 12 publications

(5 citation statements)

References 22 publications

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“…According to Velasco et al . [ 4 ], 85% of gastric GISTs involve a extragastric mass and 7% grew exophytically. Therefore, a relatively large GIST may develop extramurally, and its weight may cause traction and twisting of the intestine.…”

Section: Discussionmentioning

confidence: 99%

Gastric volvulus associated with shrinkage of a gastrointestinal stromal tumor by neoadjuvant imatinib: a case report

et al. 2023

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Background During neoadjuvant chemotherapy for giant gastrointestinal stromal tumors, changes in gastrointestinal stromal tumor size are rarely associated with events such as perforation and bleeding that require emergency surgery. Moreover, it is very rare for gastrointestinal stromal tumors to shrink and become mobile, resulting in gastric volvulus. Herein, we report a case of gastrointestinal stromal tumor shrinkage during neoadjuvant imatinib treatment, resulting in gastric volvulus that required surgery. To the best of our knowledge, this is the first reported occurrence of gastric volvulus during neoadjuvant imatinib treatment for a giant gastrointestinal stromal tumor. Case presentation A 58-year-old Japanese woman who was diagnosed with a giant gastric gastrointestinal stromal tumor and administered neoadjuvant imatinib presented to our hospital with complaints of abdominal pain and retching. Enhanced computed tomography revealed that the gastrointestinal stromal tumor had shrunk and shifted in position, and the stomach had organoaxially twisted. Accordingly, the patient was diagnosed with gastric volvulus caused by a gastric gastrointestinal stromal tumor. Conservative treatment did not improve the volvulus; hence, laparotomy was performed. The tumor developed from the lesser curvature of the stomach and caused rotation of the gastric body. The local gastric wall was resected. Histopathological examination confirmed the diagnosis of gastrointestinal stromal tumor. The patient received adjuvant imatinib for 3 years and has been alive for 5 years without recurrence. Conclusions Gastric volvulus can be caused by the laxity of the ligaments that hold the stomach and gastric ptosis or esophageal hernia and diaphragmatic hernia; therefore, gastric gastrointestinal stromal tumors rarely cause gastric volvulus. However, a risk of torsion exists if the gastrointestinal stromal tumor develops extramural to lesser curvature and attains a certain size.

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Section: Discussionmentioning

confidence: 99%

Gastric volvulus associated with shrinkage of a gastrointestinal stromal tumor by neoadjuvant imatinib: a case report

et al. 2023

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“…GISTs are usually associated with abdominal pain, palpable mass, and/or GI bleeding, accompanied by fever, anorexia, weight loss, and/or anemia [5] . Approximately 10% of GISTs are located in the jejunum [6] . The most commonly reported clinical symptoms are bleeding and obstruction [7] .…”

Section: Discussionmentioning

confidence: 99%

Acute diffuse peritonitis due to spontaneous rupture of a primary gastrointestinal stromal tumor of the jejunum: A case report

Sato

Tazawa

Fujisaki

et al. 2017

International Journal of Surgery Case Reports

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“…Colon, rectum, appendix (together 5%) and esophagus (2-3%) are rare sites (8). Velasco et al (9) reported that the jejunal GIST accounts for approximately 10% of all cases. There are also sporadic reports of GISTs arising from the omentum, mesentery or retroperitoneum, unrelated to the GI tract, but most of GISTs in these sites are from gastric or intestinal metastases.…”

Section: Discussionmentioning

confidence: 99%