Abstract:In the present work, the development of a combined specialized scanning ion-conductance microscope (SICM) and fluorescence microscope for non-invasive topographical and optical studies on soft samples immersed in electrolyte solution is reported. In SICM, the scanning probe is an electrolyte-filled glass-nanopipette with a tip aperture diameter of about 50 nanometers. Conductivity of an ionic current through the tip, driven by electrodes inside and outside of the pipette, depends on the distance between tip an… Show more
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