Scanning Imaging of Magnetic Nanoparticles for Quantitative Molecular Imaging

Force‐Induced Remnant Magnetization Spectroscopy for Specific Magnetic Imaging of Molecules

“…For example, the scanning magnetic imaging technique developed recently relies on a washing process to physically remove nonspecifically bound magnetic particles. [8] Alternatively, magnetic relaxation contrast measures the different relaxation times of free versus bound magnetic particles. [9] The associated shortcomings include a small difference in relaxation times and the lack of quantitatively resolving multiple relaxation processes.…”

“…Combining FIRMS with scanning magnetic imaging, which provides the spatial information of magnetic signals in addition to magnetization, [8,11] we were able to obtain both the quantity and location of a specific group of magnetic particles. First, a magnetization of 2.5 10 À10 Am 2 at a force of zero corresponds to 2 mg of particles, which contains 2.0 10 5 particles.…”

Force‐Induced Remnant Magnetization Spectroscopy for Specific Magnetic Imaging of Molecules

“…Combining FIRMS with scanning magnetic imaging, which provides the spatial information of magnetic signals in addition to magnetization, [8,11] we were able to obtain both the quantity and location of a specific group of magnetic particles. First, a magnetization of 2.…”

“…For example, the scanning magnetic imaging technique developed recently relies on a washing process to physically remove nonspecifically bound magnetic particles. [8] Alternatively, magnetic relaxation contrast measures the different relaxation times of free versus bound magnetic particles. [9] The associated shortcomings include a small difference in relaxation times and the lack of quantitatively resolving multiple relaxation processes.…”

Cover Picture: New Fluorinated Rhodamines for Optical Microscopy and Nanoscopy (Chem. Eur. J. 15/2010)

“…Consequently, no selectivity for target molecules has been achieved without sample separation. For example, the scanning magnetic imaging technique developed recently relies on a washing process to physically remove nonspecifically bound magnetic particles 8. Alternatively, magnetic relaxation contrast measures the different relaxation times of free versus bound magnetic particles 9.…”