Scanning electron microscopy of explanted cosmetic iris implants

Iritis, glaucoma and corneal decompensation associated with BrightOcular cosmetic iris implant

“…Inappropriately sized anterior chamber implants deleteriously affect corneal endothelial cell counts and angle structures. Surface irregularities contributed to uveitis and trabecular meshwork damage as shown by scanning electron microscopy 4. BrightOcular with the patented grooves may have partially corrected some of the problems inherent with NewColorIris.…”

“…Mechanisms of uveitis include chafing of the hinges with the iris periphery, chafing of the diaphragm with the iris body, surface irregularities of the implant causing iris irritation 4. Corneal endothelial loss results in corneal oedema and permanent visual loss from glaucoma, iritis and implant-corneal touch at the periphery.…”

Serious ocular complications of cosmetic iris implants in 14 eyes

“…Many authors 5,8,10 also found pigment dispersion throughout the anterior segment, thus speculating that pigment dispersion may be the primary mechanism of elevated IOP. Castanera et al 13 report irregularities in the implant surface on scanning electron microscopy. They speculate that these irregularities might promote contact between the implant and the iris, thus enhancing pigment dispersion.…”

Acute endothelial failure after cosmetic iris implants (NewIris®)

“…The second is the pigment dispersion due to contact between the lens and the iris, which can lead to occlusion of the trabecular meshwork. Castanera et al7 reported some irregularities in the NewIris surface by scanning electron microscopy. These irregularities can promote the contact between the lens and the iris, enhancing the pigment dispersion.…”