Scan optimization of gadolinium contrast-enhanced three-dimensional MRA of peripheral arteries with multiple bolus injections and in vitro validation of stenosis quantification

Westenberg, Jos J.M.; Wasser, Martin; Geest, Rob J. van der; Pattynama, Peter M. T.; Roos, Albert de; Vanderschoot, J.; Reiber, Johan H. C.

doi:10.1016/s0730-725x(98)00152-0

Cited by 29 publications

(30 citation statements)

References 26 publications

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“…Furthermore, we reduced the flip angle to 20°because, according to the hardware automated estimation of the signal-to-noise ratio, this was the optimal flip angle for the given MR imaging parameters. This value is also near the theoretic optimum of 25°to 55° (16). Total examination time ranged from 45 to 55 minutes.…”

Section: Sensitivity-encoded Mr Angiographysupporting

confidence: 50%

Peripheral Arterial Disease: Sensitivity-encoded Multiposition MR Angiography Compared with Intraarterial Angiography and Conventional Multiposition MR Angiography

Bezooijen¹,

Bosch²,

Tielbeek³

et al. 2004

Radiology

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A sensitivity-encoded magnetic resonance (MR) angiography protocol was developed in which imaging times in the pelvic and upper-leg positions were reduced and isotropic submillimeter voxel volumes were acquired in the lower-leg position. To achieve this, sensitivity encoding and random central-k-space segmentation in a centric filling order were applied. Results with this technique were compared with those with midstream aortic digital subtraction angiography (DSA) (as the reference standard) and conventional MR angiography in 15 patients with peripheral vascular disease. The results show that sensitivity-encoded MR angiography demonstrates increased diagnostic accuracy in comparison to that with conventional MR angiography and depicts more open infragenual arterial segments compared with both midstream aortic DSA and conventional MR angiography.

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Section: Sensitivity-encoded Mr Angiographysupporting

confidence: 50%

Peripheral Arterial Disease: Sensitivity-encoded Multiposition MR Angiography Compared with Intraarterial Angiography and Conventional Multiposition MR Angiography

Bezooijen¹,

Bosch²,

Tielbeek³

et al. 2004

Radiology

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“…Unfortunately, spatial resolution in the peripheral arteries often is restricted by insufficient signal‐to‐noise (S/N) and contrast‐to‐noise (C/N) in the more distal parts of the field of view (FOV) (4, 16, 17). In looking to overcome problems associated with insufficient S/N and C/N, various authors have advocated either single injections of high‐dose gadolinium contrast agents (1, 2, 5, 6, 10) or cumulative dosing with injections at two or more stations along the vascular territory (3, 12, 18, 19). Drawbacks of these approaches, however, include increased costs for contrast agents and, when multiple dosing protocols are used, problems associated with degraded image quality following the second injection due to residual gadolinium from the first injection (4, 18).…”

mentioning

confidence: 99%

Contrast‐enhanced MR angiography of the run‐off vasculature: Intraindividual comparison of gadobenate dimeglumine with gadopentetate dimeglumine

Knopp

Giesel

Tengg-Kobligk

et al. 2003

Magnetic Resonance Imaging

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Purpose:To compare intraindividually gadobenate dimeglumine (Gd-BOPTA) with gadopentetate dimeglumine (Gd-DTPA) for multi-station MR Angiography of the run-off vessels. Materials and Methods:Twenty-one randomized healthy volunteers received either Gd-BOPTA or Gd-DTPA as a first injection and then the other agent as a second injection after a minimum interval of 6 days. Each agent was administered at a dose of 0.1 mmol/kg bodyweight followed by a 25-mL saline flush at a single constant flow rate of 0.8 mL/second. Images were acquired sequentially at the level of the pelvis, thigh, and calf using a fast three-dimensional (3D) gradient echo sequence. Source, subtracted source, maximum intensity projection (MIP), and subtracted MIP image sets from each examination were evaluated quantitatively and qualitatively on a segmental basis involving nine vascular segments.Results: Significantly (P Ͻ 0.05) higher signal-to-noise and contrast-to-noise ratios were noted for Gd-BOPTA compared to Gd-DTPA, with the more pronounced differences evident in the more distal vessels. Qualitative assessmentrevealed no differences in the abdominal vasculature, a preference for Gd-BOPTA in the pelvic vasculature, and markedly better performance for Gd-BOPTA in the femoral and tibial vasculature. Summation of individual diagnostic quality scores for each segment revealed a significantly (P ϭ 0.0001) better performance for Gd-BOPTA compared to Gd-DTPA. Conclusion:Greater vascular enhancement of the run-off vasculature is obtained after Gd-BOPTA, particularly in the smaller more distal vessels. Enhancement differences are not merely dose dependent, but may be due to different vascular enhancement characteristics of the agents.

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“…The pre-requisite for this is to optimise the injection time on the basis of each patient's cardio-circulatory parameters, as also shown by Westenberg et al [13]. New magnets, fast informazioni sui vasi del piede rispetto alle sequenze con mezzo di contrasto anche se hanno consentito uno studio di questa regione con maggiore dettaglio ed un campo di vista più ampio (Fig.…”

Section: Discussionunclassified

“…La condizione imprescindibile su cui si fonda questa affermazione è l'ottimizzazione del tempo di iniezione ad ogni singolo paziente, in base ai suoi parametri cardio-circolatori come dimostrato anche da Westenberg et al [13]. I nuovi magneti, le sequenze veloci, i gradienti più elevati ed i nuovi sequences, higher gradients, and new software have made MRA an increasingly fast and precise examination, to the point of enabling the study of small-calibre vessels, such as those of the leg and foot.…”

Section: Conclusioniunclassified

Peripheral arterial occlusive disease: role of MR angiography

et al. 2006

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Scan optimization of gadolinium contrast-enhanced three-dimensional MRA of peripheral arteries with multiple bolus injections and in vitro validation of stenosis quantification

Cited by 29 publications

References 26 publications

Peripheral Arterial Disease: Sensitivity-encoded Multiposition MR Angiography Compared with Intraarterial Angiography and Conventional Multiposition MR Angiography

Peripheral Arterial Disease: Sensitivity-encoded Multiposition MR Angiography Compared with Intraarterial Angiography and Conventional Multiposition MR Angiography

Contrast‐enhanced MR angiography of the run‐off vasculature: Intraindividual comparison of gadobenate dimeglumine with gadopentetate dimeglumine

Peripheral arterial occlusive disease: role of MR angiography

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