Scalp metastasis from squamous cell carcinoma of the cervix

Maheshwari, G. K.; Baboo, H. A.; Ashwathkumar, R.; Dave, Kalpana; Wadhwa, Manish

doi:10.1046/j.1525-1438.2001.00074.x

Cited by 28 publications

(28 citation statements)

References 12 publications

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“…Batson’s vertebral venous plexus consists of four interconnected venous networks surrounding the vertebral column. These valveless, thin walled, low pressure veins bypass the pulmonary, caval and portal venous systems, so this could provide an aberrant pathway of haematogenous spread by tumor in the pelvis to the head and neck [32-34]. …”

Section: Discussionmentioning

confidence: 99%

Isolated cutaneous metastasis of uterine leiomyosarcoma: case report and review of literature

et al. 2012

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A 54 year old lady presented for routine excision of a scalp lesion thought clinically to represent a sebaceous cyst of the right occiput. 4 years earlier she underwent total abdominal hysterectomy and right salpingo-oophorectomy for 3 large uterine fibroids. Histo-pathological examination of the hysterectomy specimen revealed an incidental low-grade leiomyosarcoma. Staging imaging was negative for metastatic disease. She made an uneventful recovery and was treated further by adjuvant pelvic radiotherapy.She noticed an uncomfortable and unsightly cystic swelling on her occiput four years after hysterectomy and was referred for routine excision of what was believed to be a benign lesion. The lesion was excised and sent for histopathological examination. Microscopic analysis including immuno-histochemistry demonstrated an ER and PR positive metastatic deposit of leiomyosarcoma. The margins of excision were histologically clear of disease.At Multi-Disciplinary Team (MDT) discussion a diagnosis of metastatic scalp deposit from previous uterine leiomyosarcoma was made. Re-staging CT brain, thorax, abdomen and pelvis and MRI brain were negative for local recurrence or distant metastases. She is currently undergoing radiotherapy to the scalp and surrounding tissues and will be followed up closely by the involved teams.To the best of our knowledge, this is the first case described in the worldwide literature of isolated cutaneous metastasis to the scalp of uterine leiomyosarcoma without evidence of disseminated disease at other sites.Virtual slidesThe virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/1311834987345566.

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Section: Discussionmentioning

confidence: 99%

Isolated cutaneous metastasis of uterine leiomyosarcoma: case report and review of literature

et al. 2012

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“…The first reported case of ULMS with scalp metastases was described by Gardiner in 1917, and in this case the patient had perished and autopsy showed widespread metastasis involving the lungs, liver, pancreas, and bone. One theory postulated by several authors explains how a uterine leiomyosarcoma that could metastasize to the scalp haematogenously spreads via Batson's Plexus as these valveless, thin-walled, low pressure veins bypass the pulmonary, caval, and portal venous systems and provides an aberrant pathway of haematogenous spread by tumor in the pelvis to the head and neck [22][23][24].…”

Section: Discussionmentioning

confidence: 99%

Extensively Metastatic Vaginal Stump Leiomyosarcoma after Total Hysterectomy: A Rare Presentation—A Case Report with Review of Literature

Singhal

Jain

Saxena

et al. 2015

Indian J Gynecol Oncolog

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The incidence of leiomyosarcoma in uterine leiomyomas is estimated to be between 0.13 and 0.29 % [1]. However, the exact incidence of leiomyosarcoma in uteri removed with a pre-operative diagnosis of benign uterine leiomyomas has not been previously reported. In our study, we describe a case of a 58-year-old female who underwent total hysterectomy 10 years back for uterine leiomyoma and now presented to us with complaints of multiple body swellings over abdomen, arms, neck, scalp, and proptosis. On computed tomography, it was seen that there was a mass in abdomen arising from vaginal stump involving bladder, rectum with skin, muscle, omental, lung, liver, adrenal, and retroperitoneal metastases. Excisional biopsy from a parietal wall swelling and punch biopsy from the vaginal stump were taken. The final histopathological report confirmed it to be leiomyosarcoma with metastases all over the body. Combination chemotherapy of gemcitabine and docetaxel was given to patient. Patient responded to treatment on a 6 month follow-up.

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“…Cutaneous metastasis of cervical cancer is common at the abdominal wall, vulva, and anterior chest wall2; however, cases presenting at the scalp3,4, extremities5, umbilical surgical scar6,7, and drainage site8 have been reported. Only a few cases have been previously reported in Korean literature (Table 1)9-11.…”

Section: Discussionmentioning

confidence: 99%

Vulval Metastasis from Squamous Cell Carcinoma of the Cervix Clinically Presenting as Lymphangioma Circumscriptum

et al. 2011

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Patients with cervical cancer may develop local recurrence or distant metastasis, and the rate of these events is increased in proportion to the clinical stage. Cutaneous metastasis of cervical cancer is very rare and only a few cases have been reported in Korean literature. It is common at the abdominal wall, vulva, and anterior chest wall and mainly presents as an asymptomatic dermal or subcutaneous nodule, ulcer or plaque. We herein report on an interesting case of vulval metastasis from squamous cell carcinoma of the cervix with an unusual clinical manifestation resembling lymphagioma circumscriptum.

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Scalp metastasis from squamous cell carcinoma of the cervix

Cited by 28 publications

References 12 publications

Isolated cutaneous metastasis of uterine leiomyosarcoma: case report and review of literature

Isolated cutaneous metastasis of uterine leiomyosarcoma: case report and review of literature

Extensively Metastatic Vaginal Stump Leiomyosarcoma after Total Hysterectomy: A Rare Presentation—A Case Report with Review of Literature

Vulval Metastasis from Squamous Cell Carcinoma of the Cervix Clinically Presenting as Lymphangioma Circumscriptum

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