Scalp Hamartoma in Identical Twins

Rk, Simpson; Jc, Goodman; Re, George; Jp, Laurent; Wr, Cheek

doi:10.1159/000120707

Cited by 4 publications

(6 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The etiology of meningothelial hamartomas has yet to be proven but the most likely explanation is that an extrusion of meningothelial elements from the intracranial contents occurs through an abnormal extracranial communication [1,6]. With time, the communication then becomes attenuated and atretic and ultimately separates [1,6].…”

Section: Discussionmentioning

confidence: 99%

“…Scalp hamartomas with meningeal components have been misdiagnosed in the past as meningiomas, meningoceles, hemangiomas, lymphangiomas, and angiosarcoma all with drastically different treatments and outcomes [2]. Ectopic meningothelial tumors are sequestrations of meningeal tissue without glial or neural elements [6]. The majority of these tumors do not penetrate the skull but are often confused with communicating anomalies.…”

mentioning

confidence: 99%

See 1 more Smart Citation

Meningothelial hamartoma of the scalp: two case reports and literature review

et al. 1996

View full text Add to dashboard Cite

Meningothelial hamartomas are rare congenital scalp lesions composed of an admixture of cells including the meningothelial cell type. Histologically they are characterized as lesions with proliferative connective tissue, epitheloid cells forming interanastamosing vascular channels, and meningothelial elements. Lopez first described these lesions in 1974 and since that time a total of 32 cases have been reported [3]. In previous reports, they have been referred to as hamartomas with ectopic meningothelial elements, sequestered or rudimentary meningocele, and ectopic meningioma [1,3,5]. Two additional cases of meningothelial hamartomas are discussed as to their clinical presentation, work up, pathological findings at excision, and outcome. A persistent connection with the central nervous system remains a primary concern and mandates adequate preoperative testing to exclude this possibility.

show abstract

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

Meningothelial hamartoma of the scalp: two case reports and literature review

et al. 1996

View full text Add to dashboard Cite

show abstract

“…We also considered as one of possible explanations, ectopic meningeal hamartoma. This type of tumor is described as very rare lesion usually placed in the nasal region and in the scalp 12 . Meningeal cells may have a hamartomatous congenital origin and undergo transformation to neoplastic cells.…”

Section: Figure 4 -Ema Positive Meningothelial Islands (X10)mentioning

confidence: 99%

Neoplastic, hiperplastic or ectopic meningothelial islands?: Case report and short review of the literature

Milenković¹,

Berisavac²,

Jovanović³

et al. 2011

Mat Med

View full text Add to dashboard Cite

The case of concomitant occurrence of schwannoma of the ethmoid sinus and meningothelial hyperplasia in female patient without neurofibromatosis-2 is presented. The components of schwannoma tissue and meningothelial hyperplasia cells islets were confirmed by histopathological and immunohistochemical examinations. Transitional zones of these two different tissues macroscopically as well as microscopically were not observed. Histological and immunohistochemical findings and possible pathogenesis of this uncommon tumor combination is discussed. ApstraktPrikazujemo slučaj istovremene pojave švano-ma etmoidnog sinusa i meingotelijalne hiperplazije kod pacijentkinje bez neurofibromtoze. Postojanje švanoma i meningotelijalne hiperplazije je potvrđe-no histopatološkom analizom i imunohistohemijskim bojenjima. Prelazna zona između ova dva entiteta nije utvrđena, ni makroskopski ni mikroskopski. Histološki i imunohistohemijski nalaz, kao i moguća patogeneza ove retke tumorske kombinacije je predmet diskusije.

show abstract

“…Recently Simp son ct al. [18] reported identical twins affected with scalp hamartomas, which perhaps belong to the group of abor tive cephaloceles. Atretic cephaloceles have been docu mented as isolated or associated with diverse occult CNS malformations that are relevant to the description of these lesions [3,4], The association of diverse types of cephalo cele with the Dandy-Walker malformation has been noted in about 10% of the cases [2,[19][20][21][22][23].…”

Section: Cephalocelesmentioning

confidence: 99%

Familial Occurrence of Atretic Cephaloceles

Martínez‐Lage¹,

A²,

Poza³

et al. 1996

Pediatr Neurosurg

View full text Add to dashboard Cite

In this article we report the cases of an 11-year-old girl who presented with an occipital atretic cephalocele and 2 of her siblings who had similar occipital lesions. Neuroimaging studies in these three instances showed a spectrum of posterior fossa cystic malformations. The girl’s parents and a further sibling were also investigated by neuroimaging studies that proved to be normal. The familial occurrence of cephaloceles in general, and of atretic cephaloceles in particular, seems to be very rare in the absence of a known syndrome. Current literature on the familial presentation of cephaloceles and of Dandy-Walker complex is briefly reviewed. To the best of our knowledge this is the first description of the familial presentation of atretic cephaloceles not associated with a recognized syndrome.

show abstract

Scalp Hamartoma in Identical Twins

Abstract: Identical twin male infants had scalp hamartomas removed from the occipital region. The histologic features and genetic implications of these unusual lesions are discussed.

Cited by 4 publications

References 10 publications

Meningothelial hamartoma of the scalp: two case reports and literature review

Meningothelial hamartoma of the scalp: two case reports and literature review

Neoplastic, hiperplastic or ectopic meningothelial islands?: Case report and short review of the literature

Familial Occurrence of Atretic Cephaloceles

Contact Info

Product

Resources

About