Scalp carriage of<i>Pityrosporum</i>species: The effect of physiological maturity, sex and race

Noble, W. C.; Midgley, G.

doi:10.1080/00362177885380311

Cited by 22 publications

(4 citation statements)

References 7 publications

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“… 10 The SD/D condition occurs only in sebaceous lipid‐rich regions of the body (that have terminal hairs) such as scalp, and facial areas such as eyebrows and mustaches. SD/D does not become prevalent in susceptible individuals until after puberty, 11,12 most likely because sebaceous lipid synthesis is hormonally controlled and is minimal prepuberty. The sebaceous lipids are a food source for Malassezia ; these organisms are only commensal in areas of the body that produce such lipids 13 .…”

Section: Discussionmentioning

confidence: 99%

Treatment of seborrheic dermatitis of the scalp

Schwartz¹

2007

J of Cosmetic Dermatology

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Summary Background Seborrheic dermatitis and dandruff are common conditions dominated by flakes and itch symptoms. Beyond these observable conditions, the epidermis is highly perturbed and in an inflammation‐driven hyperproliferative condition. Aims This review covers current etiologic models and therapeutic strategies. Conclusion Etiology has been controversial in the past due to the search for a singular cause. There are three interrelated factors: Malassezia yeast, sebaceous lipids, and a group of host factors. The yeast and sebaceous lipids interact to yield an inflammatory initiator that leads to hyperproliferation within the epidermis; immature stratum corneum cells are dislodged as large clumps rather than a normal desquamative process. While many therapeutic strategies are theoretically possible, current technology is centered around controlling the Malassezia population. The most convenient and therefore most common format is the shampoo. A wide range of active materials are available; some are more effective than others. Even within a given active, product pharmacology can have a substantial impact on the delivered efficacy, with factors such as amount deposited on the scalp surface and bioavailability of the deposited material being relevant. Beyond choice of active and effective scalp delivery, product usage habits can substantially modulate the efficacy realized by the user.

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Section: Discussionmentioning

confidence: 99%

Treatment of seborrheic dermatitis of the scalp

Schwartz¹

2007

J of Cosmetic Dermatology

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“…Overall, the anova indicated a significant difference among the age groups for both the mean c.f.u. (F [5,238] 0/7.714; P B/0.0001) and the adjusted c.f.u. (F [5,239] 0/9.997; P B/0.0001).…”

Section: Recovery Of Malassezia Species From Individuals Of Differentmentioning

confidence: 99%

“…While Malassezia species tend to colonize lipid-rich body sites such as the chest, back, face and scalp [3], the relationship between colonization patterns and age group is less clear. A number of studies indicate that there is a difference in the colonization pattern of Malassezia species in different age groups, with an increase in colonization appearing to occur at puberty when quantities of skin lipids increase [4,5]. In addition, when colonization does occur in children, it appears to more likely to happen on the head than on the trunk [6].…”

Section: Introductionmentioning

confidence: 99%

Prevalence ofMalasseziaspecies on various body sites in clinically healthy subjects representing different age groups

Gupta

Kohli

2004

Med Mycol

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To investigate the distribution of Malassezia species on four body sites (scalp, forehead, chest and back), we employed contact plates filled with Leeming-Notman agar to sample 245 clinically healthy subjects, representing six age groups (AG) (AG I, 0-3 years; AG II, 4 14 years; AG III, 15-25 years; AG IV, 26-40 years; AG V, 41-60 years; AG VI, over 60 years). The number of colony forming units was recorded for every plate positive for Malassezia species, and the species were identified. Younger individuals (< 14 years) yielded a culture positive for Malassezia significantly less frequently than did older individuals (> or = 15 years). M. globosa was cultured at significantly elevated frequency on younger subjects. M. sympodialis was present at low frequency on younger subjects, but was found in higher amounts on the skin of adolescents and adults. The amount and kind of Malassezia species that can be recovered from human skin varies with age and body site.

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“…The sampling of microorganisms on hair, without removal, can be accomplished by a hairbrush (NOBLE and MIDGLEY 1978). Sampling by cellophane tape or canoacrylate glue are alternatives.…”

Section: F Miscellaneous Techniquesmentioning

confidence: 99%

Pharmacology of the Skin II

1989

Handbook of Experimental Pharmacology

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PrefaceThe recent interest in the pharmacology of the skin and the treatment of its diseases has come about for two reasons. The first is a realisation that many aspects of pharmacology can be studied as easily in human skin as in animal models, where they may be more relevant to human physiology and disease. Examples of this are the action of various vasoactive agents and the isolation of mediators of inflammation after UV irradiation and antigen-induced dermatitis. The second reason is the fortuitous realisation that a pharmacological approach to the treatment of skin disease need not always await the full elucidation of aetiology and mechanism. For example, whilst the argument continued unresolved as to whether the pilo-sebaceous infection which constitutes acne was due to a blocked duct or to a simple increase in sebum production, 13-cis retinoic acid, was found quite by chance totally to ablate the disease; again, whilst cyclosporin, fresh from its triumphs in organ transplantation, has been found able to suppress the rash of psoriasis, it has resuscitated the debate on aetiology.We are therefore entering a new era in which the pharmacology and clinical pharmacology of skin are being studied as a fascinating new way of exploring questions of human physiology and pharmacology as well as for the development and study of new drugs, use of which will improve disease control and at the same time help to define pathological mechanisms.It was because of this burgeoning interest in pharmacology of skin and its diseases, that this book came about. Indeed it is long overdue and was planned several years ago; we console ourselves with the thought that the delay may have served to help define certain principles which were then only just emerging.The book is divided into two volumes which are independent but complementary; the first being an account of the general pharmacology of skin, the second volume being more concerned with disease and drugs. The first volume is divided into two parts, the one dealing with the pharmacology of skin systems and their control and the other with autocoids in normal and inflamed skin. This second volume has three parts; the first part deals with the methods of measurement which are becoming of increasing importance both in studying the pharmacological effects of drugs and the clinical pharmacology of skin; the second deals with toxicology in its widest sense -including metabolism and percutaneous absorption; and the third is an account both of specific drugs and the drugs used for specific diseases.

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Scalp carriage ofPityrosporumspecies: The effect of physiological maturity, sex and race

Cited by 22 publications

References 7 publications

Treatment of seborrheic dermatitis of the scalp

Treatment of seborrheic dermatitis of the scalp

Prevalence ofMalasseziaspecies on various body sites in clinically healthy subjects representing different age groups

Pharmacology of the Skin II

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