In this paper, high-efficient lifting-based architectures for the 5/3 discrete wavelet transform (DWT) are proposed. The proposed parallel and pipelined architecture consists of a horizontal filter (HF) and a vertical filter (VF). The system delays of the proposed architectures are reduced. Filter coefficients of the biorthogonal 5/3 wavelet low-pass filter are quantized before implementation in the high-speed computation hardware. In the proposed architecture, all multiplications are performed using less shifts and additions.The proposed architecture is 100% hardware utilization and ultra low-power. The architecture has regular structure, simple control flow, high throughput and high scalability. Thus, it is very suitable for newgeneration image compression systems, such as JPEG-2000.