Scalable production of CuInS₂/ZnS quantum dots in a two-step droplet-based microfluidic platform

Abstract

We report the scalable formation of CuInS2/ZnS nanocrystals using a two-stage microfluidic reactor integrated with a real-time optical detection system, which is able to monitor reaction parameters prior and subsequent to the addition of the shell material.

Continuous Synthesis of Nanocrystals via Flow Chemistry Technology

“…High‐boiling‐point solvents, such as OA, ODE, and trioctylphosphine are widely used, and thus the reaction systems are viscous at room temperature. Because the particle size and their absorption or emission spectra has correspondence, online spectrum detecting systems have been built to monitor the particle size variation during the reaction . In addition, to prevent from being oxidized and aggregation, it is relatively easy to maintain the high demands on water and air blocking environment in the continuous microreactors.…”

“…Furthermore, bio‐macromolecule surface modification can reduce the toxicity of QDs and make them more easily combined with specific locations of organisms. Therefore, surface modifications with amine acid,143b carbohydrate, and protein have also been tested by the ligand exchange units in microreaction system.…”

Microfluidic assisted synthesis of PLGA drug delivery systems

“…Two-stage microuidically synthesis has been reported to control the core and shell more precisely in the production inorganic NPs. 121,122 Such multi-stage could be advantageous in the production of PLGA-based DDSs with sophisticated features. Moreover, screening and preclinical test of drugs in living cells are crucial steps in drug discovery, direct purication and cell treatment on the microuidic platform could be considered as additional steps toward the increased efficacy and speed.…”

Transient bioelectrical devices inspired by a silkworm moth breaking out of its cocoon

“…In this paper, the preparing process of the heat-sensitive microspheres with a 9.3 mol L À1 LiBr solution in wax shells is similar to that of the double emulsions based on microuidic technology. [23][24][25][26] The capillary microuidic device was assembled by coaxially aligning two cylindrical capillaries inside a square capillary, as shown in Fig. 2.…”