Scalability, reliability, and validity of the benzodiazepine dependence self-report questionnaire in outpatient benzodiazepine users

Kan, Cornelis C.; Breteler, M.H.M.; Timmermans, Elisabeth; Ven, A.H.G.S. van der; Zitman, Frans G.

doi:10.1016/s0010-440x(99)90129-3

Cited by 38 publications

(43 citation statements)

References 16 publications

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“…Three dependence dimensions were derived: (1) awareness of problematic use, (2) preoccupation with the availability of benzodiazepines, and (3) lack of compliance with the therapeutic regimen. 25 The Bendep-SRQ has good scalability, reliability, and validity in general practice patients 26 and in psychiatric outpatients. 27 …”

Section: Benzodiazepine Usementioning

confidence: 99%

Long-Term Benzodiazepine Use and Salivary Cortisol

Manthey¹,

Giltay²,

Neven³

et al. 2010

Journal of Clinical Psychopharmacology

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Section: Benzodiazepine Usementioning

confidence: 99%

Long-Term Benzodiazepine Use and Salivary Cortisol

Manthey¹,

Giltay²,

Neven³

et al. 2010

Journal of Clinical Psychopharmacology

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“…The BZD dependence self-report questionnaire (Bendep-SRQ) (Kan, Breteler, Timmermans, van der Ven, & Zitman, 1999), asks subjects to determine the extent of their agreement with statements such as, "The medication is getting me into trouble" (p. 287); or "I get nervous if my medication is out of reach" (p. 287); or "I would like to give up taking the medication" (p. 287). The BZD Dependence Questionnaire (Baillie & Mattick, 1996) asks: "Have you felt an urge or desire to take sedatives, tranquilizers or sleeping pills in the last month?"…”

mentioning

confidence: 99%

Factors Associated with Self-Rated Benzodiazepine Addiction among Community-Dwelling Seniors

Voyer

Préville

Martin

et al. 2011

Journal of Addictions Nursing

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Long-term use of benzodiazepines carries considerable personal consequences such as memory loss and functional impairment. In addition, use over time may bring about dependence and habituation thus leading older persons to believe they cannot discontinue the drug and to experience withdrawal symptoms should its use suddenly cease. The frequency of such negative consequences remains unclear. The purpose of this study is to determine the prevalence of self-rated addiction among older persons and its associated factors. Face-to-face computer-assisted interviews were conducted in the homes of 2,785 persons aged 65 years and over, randomly selected from across the Province of Quebec, Canada. Of the 707 users of benzodiazepines, 43% considered themselves addicted. They were more likely to be 75 years or over, to suffer from panic disorder, to believe that health professionals are ready and available to discuss emotional problems with them, and to be less than satisfied with their social relationships. This study showed that a large proportion of benzodiazepine users rated themselves as addicted. These findings indicate that it is important for nurses to screen older adults living in the community to identify those who continue to use benzodiazepine beyond the recommended therapeutic time frame, perceive themselves to be dependent, and could potentially benefit from participation in a withdrawal program.

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“…The DDD was categorized into three groups: (i) daily dose ≤0.5 DDD (low dose), (ii) daily dose >0.5 but <1 DDD (intermediate dose), and (iii) daily dose >1 DDD (high dose). BZD users completed the BZD Dependence Self-Report Questionnaire (Bendep-SRQ) as a measure of dependence severity [21,22].…”

Section: Methodsmentioning

confidence: 99%

High dose benzodiazepines prolong reaction times in chronic users who have major depressive and/or anxiety disorders

Manthey

Loenen-Frösch

Giltay

et al. 2014

Br J Clin Pharmacol

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AIMShort term administration of benzodiazepines (BZD) was found to prolong reaction time (RT) in experimental studies. However, studies on long term BZD use did not always adjust for important confounders and showed inconsistent results. We aimed to identify a possible relationship between long term BZD use and RT in BZD users in this large cross-sectional, observational study. METHODSThe RTs of non-users (n = 2404) were compared with low (n = 288), intermediate (n = 74), and high dose BZD users (n = 57) in the Netherlands Study of Depression and Anxiety (NESDA). RTs were obtained from the Implicit Association Test. Analyses were adjusted for sociodemographic characteristics, health indicators, severity of psychopathology and antidepressant use. RESULTSOf the NESDA participants, 419 subjects (14.8%) used BZDs. A higher dose of BZDs was associated with prolonged RTs (P = 0.01). When comparing the different dose groups, the high dose group, but not the low and medium dose groups, had significantly longer RTs than the non-users. CONCLUSIONSTolerance for the RT prolonging effect of relatively high doses of BZDs does not seem to develop. As prolonged RTs can have adverse consequences in daily life, BZDs should be prescribed conservatively at the lowest possible dose. WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT• Short term benzodiazepine (BZD) use prolongs reaction time (RT).• Although the prevalence of long term BZD use is high, it in unclear whether RT is still affected in chronic use. WHAT THIS STUDY ADDS• High dose BZD use is associated with prolonged RTs in chronic users (independent of psychopathology).• Tolerance for the RT prolonging effect of BZDs does not seem to develop at high doses in chronic users.

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Scalability, reliability, and validity of the benzodiazepine dependence self-report questionnaire in outpatient benzodiazepine users

Cited by 38 publications

References 16 publications

Long-Term Benzodiazepine Use and Salivary Cortisol

Long-Term Benzodiazepine Use and Salivary Cortisol

Factors Associated with Self-Rated Benzodiazepine Addiction among Community-Dwelling Seniors

High dose benzodiazepines prolong reaction times in chronic users who have major depressive and/or anxiety disorders

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