Scaffold development using 3D printing with a starch-based polymer

Lam, Christopher; Mo, Xiumei; Teoh, Swee‐Hin; Hutmacher, Dietmar W.

doi:10.1016/s0928-4931(02)00012-7

Cited by 543 publications

(316 citation statements)

References 12 publications

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“…In addition, structured or unstructured reinforcement may be added. Well-studied hydrogel chemistries include synthetics such as acrylamide, PEG and PVA, and biopolymers such as cellulose [102] and gelatin [103]. A general review of the theory used to understand stimuli-responsive hydrogels, and the multitude of work on the subject, can be found in Koetting [104].…”

Section: Plant Tissues-volume-changementioning

confidence: 99%

Morphing in nature and beyond: a review of natural and synthetic shape-changing materials and mechanisms

2016

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Shape-changing materials open an entirely new solution space for a wide range of disciplines: from architecture that responds to the environment and medical devices that unpack inside the body, to passive sensors and novel robotic actuators. While synthetic shape-changing materials are still in their infancy, studies of biological morphing materials have revealed key paradigms and features which underlie efficient natural shape-change. Here, we review some of these insights and how they have been, or may be, translated to artificial solutions. We focus on soft matter due to its prevalence in nature, compatibility with users and potential for novel design. Initially, we review examples of natural shape-changing materials-skeletal muscle, tendons and plant tissues-and compare with synthetic examples with similar methods of operation. Stimuli to motion are outlined in general principle, with examples of their use and potential in manufactured systems. Anisotropy is identified as a crucial element in directing shape-change to fulfil designed tasks, and some manufacturing routes to its achievement are highlighted. We conclude with potential directions for future work, including the simultaneous development of materials and manufacturing techniques and the hierarchical combination of effects at multiple length scales.

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Section: Plant Tissues-volume-changementioning

confidence: 99%

Morphing in nature and beyond: a review of natural and synthetic shape-changing materials and mechanisms

2016

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“…Using a 3-D printer it would be fairly straightforward to reproduce the structure in a suitable plastic. However, current developments in 3-D printing with biopolymers (Lam et al, 2002;NASA, 2013) suggest that it might be possible to carry out such a process with a mix of protein and starch. The structure would then be built in in the printing process and the problem then becomes one of ensuring that the mechanical properties of the matrix are suitable and flavour an appearance are appropriate.…”

Section: Protein Functionality For Quality Baked Goodsmentioning

confidence: 99%

Increasing the utilisation of sorghum, millets and pseudocereals: Developments in the science of their phenolic phytochemicals, biofortification and protein functionality

Taylor

Belton

Beta

et al. 2014

Journal of Cereal Science

142

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There is considerable interest in sorghum, millets and pseudocereals for their phytochemical content, their nutritional potential and their use in gluten-free products. They are generally rich in a several phenolic phytochemicals. Research has indicated that the phenolics in these grains may have several important health-promoting properties: prevention and reduction of oxidative stress, anti-cancer, anti-diabetic, anti-inflammatory, anti-hypertensive and cardiovascular disease prevention. However, increased research on the actual healthpromoting properties of foods made from these grains is required. Biofortified (macro-and micronutrient enhanced) sorghum and millets are being developed through conventional breeding and recombinant DNA technology to combat malnutrition in developing countries.Enhanced nutritional traits include: high amylopectin, high lysine, improved protein digestibility, provitamin A rich, high iron and zinc, and improved mineral bioavailability through phytate reduction. Some of these biofortified cereals also have good agronomic characteristics and useful commercial end-use attributes, which will be important to their adoption by farmers. Knowledge of the structure of their storage proteins is increasing.Drawing on research concerning maize zein, which shows that it can produce a visco-elastic wheat-like dough, it appears that the storage proteins of these minor grains also have this potential. Manipulation of protein β-sheet structure seems critical in this regard.3

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“…As for macroporosity, it forms 3D complex structures, which encourages migration and proliferation of osteogenic cells, as well as reinforces mechanical connection with adjacent tissues [4,12,17]. Nevertheless, it has presented limitations in existing traditional technologies due to uncontrollable distribution and sizes of pores in scaffolds [18][19][20], and recently developed 3D printing techniques are not capable of producing microporosity in nano scale [21][22][23]. Hence it is almost impossible to fabricate scaffolds with refined structures consisting of porosity across macro, micron and nano scale (nm -μm -mm) through these methods.…”

Section: Introductionmentioning

confidence: 99%

Fabrication and characterization of 3D complex hydroxyapatite scaffolds with hierarchical porosity of different features for optimal bioactive performance

Chen

Zhang

Yang

et al. 2017

Ceramics International

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Scaffold development using 3D printing with a starch-based polymer

Cited by 543 publications

References 12 publications

Morphing in nature and beyond: a review of natural and synthetic shape-changing materials and mechanisms

Morphing in nature and beyond: a review of natural and synthetic shape-changing materials and mechanisms

Increasing the utilisation of sorghum, millets and pseudocereals: Developments in the science of their phenolic phytochemicals, biofortification and protein functionality

Fabrication and characterization of 3D complex hydroxyapatite scaffolds with hierarchical porosity of different features for optimal bioactive performance

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