Scabies simulating Darier disease in an immunosuppressed host

Anolik, M. A.

doi:10.1001/archderm.112.1.73

Cited by 13 publications

(3 citation statements)

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“…Other conditions that crusted scabies mimics include erythroderma, Darier’s disease, drug eruption, eczema, lichen planus, lymphoma, pityriasis rubra pilaris, and psoriasis. 15 , 28 – 40 …”

Section: Discussionmentioning

confidence: 99%

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Scabies masquerading as bullous pemphigoid: scabies surrepticius

Cohen

2017

CCID

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Scabies, a parasitic infestation caused by the mite Sarcoptes scabiei, is diagnosed by observing either the mite, its ova, or its excrement. The mite tracts, known as burrows and a characteristic presentation of the pruritic condition, are typically found on the web spaces between the fingers. Other cutaneous lesions include excoriated papules, pustules, and vesicles. However, atypical clinical variants of scabies, such as bullous, crusted, hidden, incognito, nodular, and scalp forms of the parasitic infestation, mimic the morphologic features of other non-parasitic dermatoses. A 76-year-old man presented with pruritic blisters and urticarial plaques that demonstrated not only pathology changes, but direct immunofluorescence also showed findings of bullous pemphigoid. His condition improved, but did not resolve, with topical corticosteroid cream for the management of the primary autoimmune blistering disorder. When other family members subsequently developed scabies, the correct diagnosis for his condition, bullous scabies, was established by demonstrating mites, ova, and scybala on a mineral oil preparation from a skin scraping of a newly appearing burrow. Bullous scabies can masquerade not only clinically, but also both pathologically and immunologically as bullous pemphigoid. Scabies serrupticius is introduced as a unifying term to designate all of the non-classic presentations of S. scabiei mite infestation.

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Section: Discussionmentioning

confidence: 99%

“…There is a heavy infestation of mites and this variant of scabies is very contagious. 15 , 28 – 40 [c] This subtype is also referred to as unrecognized scabies; polymerase chain reaction of cutaneous scales positive for Sarcoptes scabiei DNA. It presented as an atypical eczema in a woman following automobile accident.…”

Section: Figurementioning

confidence: 99%

Scabies masquerading as bullous pemphigoid: scabies surrepticius

Cohen

2017

CCID

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“…As a result recovered carriers (De Vos and Roos, 1983) develop patent infections. Ectoparasite immunosuppression has been observed with mite infestation (Paterson, Allen andBeveridge, 1973, Anolik andRudolph, 1976) and ticks where it affects immunological response to heterologous antigens too (Njau, unpub.). The disease reaction in some animals at Pugu was refractory to treatment and they died of the disease.…”

Section: Discussionmentioning

confidence: 99%

Treatment of field cases of East Coast fever with halofuginone lactate

Njau

Mkonyi

Mleche³

et al. 1985

Trop Anim Health Prod

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In a series of field trials 48 (55%) of 88 field cases of East Coast fever treated with halofuginone lactate recovered and survived and 40 (45%) died while 31 (86%) of 36 untreated control animals died of East Coast fever and five (14%) recovered. For cases diagnosed and treated early a 100% recovery rate was achieved. A single dose at 1.2 mg/kg body weight per os was adequate. Recovery rate was only 36% for cases diagnosed and treated at an advanced stage. Such cases required two doses at 1.2 mg/kg or a combination of 1.2 and 2.4 mg/kg body weight given at about two days interval. The temperature dropped to normal levels within 48 h of treatment and schizonts started degenerating as early as 24 h after treatment and had disappeared by 48 to 72 h. Piroplasms were not affected by the drug. Recovered animals remained free of East Coast fever for periods up to 12 months of observation despite continuous tick challenge. It was concluded that, with early detection and treatment augmented with proper tick control, outbreaks of East Coast fever can be effectively controlled with halofuginone lactate.

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Diseases Caused by Arthropods and Other Noxious Animals

Burns

2010

Rook's Textbook of Dermatology

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Scabies simulating Darier disease in an immunosuppressed host

Cited by 13 publications

References 0 publications

Scabies masquerading as bullous pemphigoid: scabies surrepticius

Scabies masquerading as bullous pemphigoid: scabies surrepticius

Treatment of field cases of East Coast fever with halofuginone lactate

Diseases Caused by Arthropods and Other Noxious Animals

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