Saussurea grandicapitula W. Lee et H. T. Im (Compositae), a New Species from the Taebaek Mountains, Korea

Lee, Woo Tchul; Im, Hyoung Tak

doi:10.11110/kjpt.2007.37.4.387

Cited by 7 publications

(6 citation statements)

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“…Circular dichroism spectra ( Figure S4) indicated that bilayer-incorporated A 4,5 GWALP23 is largely helical, which allowsc haracterization of the behavioro ft he peptideh elices in aligned bilayersb ym eans of solid-state 2 HNMR spectroscopy.T he 2 Hq uadrupolars plitting magnitudes j Dnq j from the labeled alanine CD 3 groups serve to define ap referred tilted, dynamically averagedo rientation of the core helix with respect to the bilayer normal in an appliedm agnetic field. [17] From the 2 HNMR spectra of oriented liquid crystalline peptide-lipid samples (Figure 1), it is evident that the single-tryp-tophanp eptideA 4,5 GWALP23, as well as F 4,5 GWALP23 (observed previously), [5] aligns well in the lipid bilayers and undergoes typical rapid reorientation about the bilayer normal, [21,22] yet experiencessurprisingly little additional dynamic averaging. Extensive dynamic averaging would narrow the range of j Dn q j values, [21] but the j Dn q j range for A 4,5 GWALP23 is similar to that observed for GWALP23 itself (Figure 1; additional 2 HNMR spectra for labeled alanines in the helical core of A 4,5 GWALP23 are presented in Figure S5).…”

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confidence: 55%

Juxta‐terminal Helix Unwinding as a Stabilizing Factor to Modulate the Dynamics of Transmembrane Helices

et al. 2016

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Transmembrane helices of integral membrane proteins often are flanked by interfacial aromatic residues that may serve as anchors to aid the stabilization of a tilted transmembrane orientation. Yet physical factors that govern the orientations or the dynamic averaging of individual transmembrane helices are not well understood and have not been adequately explained. When using solid-state 2H NMR spectroscopy to examine lipid bilayer-incorporated model peptides of the GWALP23 (acetyl-GGALW(LA)6LWLAGA-amide) family, we observe substantial unwinding at the terminals of several tilted helices spanning the membranes of DLPC, DMPC or DOPC lipid bilayers. The fraying of helix ends may be vital for defining the dynamics and orientations of transmembrane helices in lipid-bilayer membranes.

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confidence: 55%

Juxta‐terminal Helix Unwinding as a Stabilizing Factor to Modulate the Dynamics of Transmembrane Helices

et al. 2016

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“…It grows to approximately a height of 1 m in limestone regions. Saussurea grandicapitula has cobwebby hairs on the petioles of the radical and lower cauline leaves, big globose involucres with brown-cobwebby hairs, and recurved phyllaries [ 21 ]. Saussurea albifolia , S. diamantica, and S. seoulensis share common traits including basal rosette leaves, cobwebby hair on abaxial leaf surfaces, and white or yellowish hairs on the involucre.…”

Section: Introductionmentioning

confidence: 99%

Comparative plastomes and phylogenetic analysis of seven Korean endemic Saussurea (Asteraceae)

Yun

Kim

2022

BMC Plant Biol

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Background Saussurea is one of the most species-rich genera in the Cardueae, Asteraceae. There are approximately 40 Saussurea species distributed in Korea, with nearly 40% of them endemics. Infrageneric relationships remain uncertain due to insufficient resolutions and low statistical support. In this study, we sequenced the plastid genomes of five Korean endemic Saussurea (S. albifolia, S. calcicola, S. diamantica, S. grandicapitula, and S. seoulensis), and comparative analyses including two other endemics (S. chabyoungsanica and S. polylepis) were conducted. Results The plastomes of Korean endemics were highly conserved in gene content, order, and numbers. Exceptionally, S. diamantica had mitochondrial DNA sequences including two tRNAs in SSC region. There were no significant differences of the type and numbers of SSRs among the seven Korean endemics except in S. seoulensis. Nine mutation hotspots with high nucleotide diversity value (Pi > 0.0033) were identified, and phylogenetic analysis suggested that those Korean endemic species most likely evolved several times from diverse lineages within the genus. Moreover, molecular dating estimated that the Korean endemic species diverged since the late Miocene. Conclusions This study provides insight into understanding the plastome evolution and evolutionary relationships of highly complex species of Saussurea in Korean peninsula.

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“…The genus Saussurea in the Asteraceae family is a large and diverse group of plants that has been widely used in traditional medicine for many purposes [28][29][30]. In Korea, the Saussurea genus is highly diverse with 32 recognized species, 16 of which are endemic [31]. In this study, we isolated protocatechuic acid and syringin from the n-BuOH extracts of S. neoserrata Nakai through fractionation.…”

Section: Introductionmentioning

confidence: 99%

Protocatechuic Acid and Syringin from <em>Saussurea neoserrata</em> Nakai Attenuate Prostaglandin Production in Keratinocytes Exposed to Airborne Particulate Matter

Jeong¹,

Ju²,

Kwon³

et al. 2023

Preprint

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Saussurea neoserrata Nakai offers a reliable and efficient source of antioxidants that can help alleviate adverse skin reactions triggered by air pollutants. Air pollutants, such as particulate matter (PM), have the ability to infiltrate the skin and contribute to the higher occurrence of cardiovascular, cerebrovascular, and respiratory ailments. Individuals with compromised skin barriers are particularly susceptible to the impact of PM since it can be absorbed more readily through the skin. This study investigated the impact of protocatechuic acid and syringin, obtained from the n-BuOH extract of S. neoserrata Nakai, on the release of PGE2 and PGD2 induced by PM10. Additionally, it examined the gene expression of enzymes involved in the synthesis of PGE2 and PGD2 in human keratinocytes. The findings of this research highlight the potential of utilizing safe and efficient plant-derived antioxidants in dermatological and cosmetic applications to mitigate the negative skin reactions caused by exposure to air pollution.

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Saussurea grandicapitula W. Lee et H. T. Im (Compositae), a New Species from the Taebaek Mountains, Korea

Cited by 7 publications

References 0 publications

Juxta‐terminal Helix Unwinding as a Stabilizing Factor to Modulate the Dynamics of Transmembrane Helices

Juxta‐terminal Helix Unwinding as a Stabilizing Factor to Modulate the Dynamics of Transmembrane Helices

Comparative plastomes and phylogenetic analysis of seven Korean endemic Saussurea (Asteraceae)

Protocatechuic Acid and Syringin from <em>Saussurea neoserrata</em> Nakai Attenuate Prostaglandin Production in Keratinocytes Exposed to Airborne Particulate Matter

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